Name | Acetylcholinesterase |
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Synonyms | ACHE; ACHE protein; AChE; ARACHE; AcChoEase; Acetylcholine acetylhydrolase; Acetylcholinesterase; Acetylcholinesterase isoform E4 E6 variant… |
Name | bromophos |
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CAS |
PubMed | Abstract | RScore(About this table) | |
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7935256 | Santhoshkumar P, Shivanandappa T: Differential in vivo inhibition of the foetal and maternal brain acetylcholinesterase by bromophos in the rat. Neurotoxicol Teratol. 1994 May-Jun;16(3):227-32. |
163(2,2,2,3) | Details |
8812210 | Santhoshkumar P, Karanth S, Shivanandappa T: Neurotoxicity and pattern of acetylcholinesterase inhibition in the brain regions of rat by bromophos and ethylbromophos. Fundam Appl Toxicol. 1996 Jul;32(1):23-30. |
85(1,1,1,5) | Details |
3341046 | Shivanandappa T, Joseph P, Krishnakumari MK: Response of blood and brain cholinesterase to dermal exposure of bromophos in the rat. Toxicology. 1988 Feb;48(2):199-208. In a subacute study, daily dermal application of 50 mg/kg body weight of Bromophos for 5 and 10 days, resulted in high inhibition of the serum cholinesterase and brain acetylcholinesterase, the former being more marked which was reversible after 10 or 15 days of post-exposure period. |
82(1,1,1,2) | Details |
1595894 | Kumaran S, Tran-Minh C: Determination of organophosphorous and A flow injection system, incorporating an acetylcholinesterase (AChE) single bead string reactor (SBSR), for the determination of some organophosphorous (azinphos-ethyl, azinphos-methyl, bromophos-methyl, dichlorovos, fenitrothion, malathion, paraoxon, parathion-ethyl and parathion-methyl) and insecticides (carbofuran and carbaryl) is presented. |
insecticides by flow injection analysis. Anal Biochem. 1992 Jan;200(1):187-94.6(0,0,1,1) | Details |
10421462 | Santhoshkumar P, Shivanandappa T: In vitro sequestration of two organophosphorus homologs by the rat liver. . Chem Biol Interact. 1999 May 14;119-120:277-82. Bromophos (Bp) and ethylbromophos (EBp) are two structurally homologous organophosphorus insecticides (OP) which show a 24-fold difference in their toxicity to the laboratory rat (LD50--2215 and 91 mg/kg b.w., respectively). Bromoxon (Bo) and ethylbromoxon (EBo) were greater inhibitors of rat hepatic CaE than brain acetylcholinesterase (AChE) with IC50 values at nanomolar and picomolar levels, respectively. |
4(0,0,0,4) | Details |
985225 | Stone BF, Wilson JT, Youlton NJ: Linkage and dominance characteristics of genes for resistance to organophosphorus acaricides and allelic inheritance of decreased brain cholinesterase activity in three strains of the cattle tick, Boophilus microplus. Aust J Biol Sci. 1976 Jul;29(3):251-63. No F1 larval progeny from the following crossings were appreciably more resistant than their parents to these chemicals: R x B--bromophos ethyl and fenthion; B x M--carbaryl, chlorfenvinphos, chlorpyrifos, diazinon, dimethoate, ethion, fenthion and formothion; M x R--chlorfenvinphos, diazinon, dimethoate, ethion, formothion. F1 adult progeny of B x M and R x M crossings exhibited the incompletely recessive mutant-type decreased brain acetylcholinesterase (AChE) activity common to strains B, M and R, thus satisfying the test for allelism. |
2(0,0,0,2) | Details |
52151 | Ramisz A, Komorowski A: [Histochemical study of the effect of phosphoroorganic esters Z-50 (fenchlorfos) and Z-51 (bromophos) on cholinesteras activity in the course of the muscle phase in experimental trichinellosis in mice]. Pol Arch Weter. 1975;17(4):623-31. Z-50 and Z-51 penetrate in therapeutic doses the striated muscles rather weakly. 24 hrs after these compounds were given, acetylcholinesterase (AChE) activity was inhibited in motor end-plates in about 30%, and in muscle fibres infected with T. spiralis larvae in about 60-70%. |
2(0,0,0,2) | Details |