| Name | Acetylcholinesterase |
|---|---|
| Synonyms | ACHE; ACHE protein; AChE; ARACHE; AcChoEase; Acetylcholine acetylhydrolase; Acetylcholinesterase; Acetylcholinesterase isoform E4 E6 variant… |
| Name | carbosulfan |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 16461013 | Yi MQ, Liu HX, Shi XY, Liang P, Gao XW: Inhibitory effects of four insecticides on acetylcholinesterase of male and female Carassius auratus in vitro. Comp Biochem Physiol C Toxicol Pharmacol. 2006 May;143(1):113-6. Epub 2006 Feb 3. The ratios of bimolecular rate constant (female/male) for AChE reacting with methomyl, thiodicarb, carbofuran and carbosulfan were 1.03, 2.44, 1.03 and 1.106, respectively. |
197(2,3,3,7) | Details |
| 16753212 | Chandrasekara LW, Pathiratne A: Body size-related differences in the inhibition of brain acetylcholinesterase activity in juvenile Nile tilapia (Oreochromis niloticus) by chlorpyrifos and carbosulfan. Ecotoxicol Environ Saf. 2007 May;67(1):109-19. Epub 2006 Jun 6. Three size groups of fish (fry: 3-4 cm, fingerlings: 6-8 cm, sub-adults: 10-12 cm in total length) were exposed to a series of concentrations of chlorpyrifos (0.5-12 microg L (-1)) or carbosulfan (1-10 microg L (-1)), and concentration-response for inhibition and recovery of the AChE enzyme was evaluated in comparison to the controls at different time points, 2, 6, 10, and 14 d. |
148(1,3,3,8) | Details |
| 3710030 | Renzi BE, Krieger RI: Sublethal acute toxicity of carbosulfan [2,3-dihydro-2,2-dimethyl-7-benzofuranyl (d i-n-butylaminosulfenyl)(methyl) in the rat after intravenous and oral exposures. Fundam Appl Toxicol. 1986 Jan;6(1):7-15. Based on regression analysis and metabolic studies, both carbosulfan and carbofuran contributed to the observed AChE inhibition; however, carbofuran, a more potent in vitro inhibitor and the usual predominant inhibitor in plasma, was responsible for most of the erythrocyte AChE inhibition. |
120(1,2,3,5) | Details |
| 12680920 | N'Guessan R, Darriet F, Guillet P, Carnevale P, Traore-Lamizana M, Corbel V, Koffi AA, Chandre F: Resistance to carbosulfan in Anopheles gambiae from Ivory Coast, based on reduced sensitivity of acetylcholinesterase. Med Vet Entomol. 2003 Mar;17(1):19-25. |
82(1,1,1,2) | Details |
| 17915512 | Djogbenou L, Weill M, Hougard JM, Raymond M, Akogbeto M, Chandre F: Characterization of insensitive acetylcholinesterase (ace-1R) in Anopheles gambiae (Diptera: Culicidae): resistance levels and dominance. J Med Entomol. 2007 Sep;44(5):805-10. Furthermore, the dominance status varied between semi-recessivity with fenitrothion and chlorpyrifos methyl insecticides to semidominance with temephos, carbosulfan, and propoxur. |
2(0,0,0,2) | Details |
| 19908228 | Carletto J, Martin T, Vanlerberghe-Masutti F, Brevault T: Insecticide resistance traits differ among and within host races in Aphis gossypii. Pest Manag Sci. 2010 Mar;66(3):301-7. Molecular diagnostic (PCR-RFLP) and enzyme assays were also performed to detect the basic mechanisms underlying insecticide resistance.RESULTS: All six clones were susceptible to acetamiprid (neonicotinoid) or carbosulfan Conversely, all clones were resistant to dimethoate (organophosphate) (RF = 4.1-38.1) and carried mutation S431F in the acetylcholinesterase gene. |
1(0,0,0,1) | Details |
| 9439121 | Chandre F, Darriet F, Doannio JM, Riviere F, Pasteur N, Guillet P: Distribution of organophosphate and resistance in Culex pipiens quinquefasciatus (Diptera: Culicidae) in West Africa. J Med Entomol. 1997 Nov;34(6):664-71. Of 27 samples from Cote d'Ivoire, 25 also displayed cross resistance to carbamates as shown by a mortality plateau in bioassays with propoxur and carbosulfan (similar to chlorpyrifos). Cross resistance to organophosphates and carbamates was caused by an insensitive acetylcholinesterase allele (AceR). |
1(0,0,0,1) | Details |
| 15311465 | Corbel V, Duchon S, Zaim M, Hougard JM: Dinotefuran: a potential neonicotinoid insecticide against resistant mosquitoes. J Med Entomol. 2004 Jul;41(4):712-7. The results showed that dinotefuran was less toxic than most of the commonly used insecticides (e.g., deltamethrin, carbosulfan, and temephos) against the susceptible mosquitoes tested (between 6- and 100-fold at the LD50 level). More interestingly, the -resistant strain of Cx. quinquefasciatus was significantly more affected by dinotefuran than the susceptible strain (RR = 0.70), probably because the insensitive acetylcholinesterase is less efficient to degrade nicotinic substrates than normal acetylcholinesterase. |
1(0,0,0,1) | Details |