Protein Information

Name CYP3A4
Synonyms CP33; CYP3; HLP; CYP3A; CP34; CYP 3A4; CYP 3; CYP3A3…

Compound Information

Name carbosulfan
CAS

Reference List

PubMed Abstract RScore(About this table)
20307514 Abass K, Reponen P, Mattila S, Pelkonen O: Metabolism of carbosulfan II. Chem Biol Interact. 2010 Mar 20.

Based on average abundances of CYP enzymes in human liver, CYP3A4 contributed to 98% of carbosulfan activation, while CYP3A4 and CYP2B6 contributed 57 and 37% to detoxification, respectively.
331(4,4,5,6) Details