| Name | adenylate cyclase |
|---|---|
| Synonyms | AH related protein; HCA2; ATP pyrophosphate lyase; Adenylate cyclase; Adenylyl cyclase soluble; HCA 2; RP1 313L4.2; SAC… |
| Name | chlordimeform |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 2833825 | Costa LG, Olibet G, Murphy SD: Alpha 2-adrenoceptors as a target for formamidine pesticides: in vitro and in vivo studies in mice. Toxicol Appl Pharmacol. 1988 Apr;93(2):319-28. While the toxicity in insects of formamidines such as chlordimeform (CDM), its demethylated metabolite DCDM, and amitraz (AMZ) appears to involve activation of an -sensitive adenylate cyclase, their mechanism of action in mammals remains elusive. |
81(1,1,1,1) | Details |
| 6306370 | Gole JW, Orr GL, Downer RG: Interaction of formamidines with -sensitive adenylate cyclase receptor in the nerve cord of Periplaneta americana L. Life Sci. 1983 Jun 27;32(26):2939-47. Chlordimeform (CDM) and demethylchloridimeform (DCDM) mimic the action of in elevating adenylate cyclase activity in intact nerve cords of the American cockroach, Periplaneta americana. |
8(0,0,1,3) | Details |
| 2747629 | Nathanson JA: Development of a photoaffinity ligand for receptors. . Mol Pharmacol. 1989 Jul;36(1):34-43. This binding is reduced by prior incubation with agonists, including demethyl-chlordimeform, and 2-(phenylimino) imidazolidines, but not by or Under reversible conditions NC-5Z is a full agonist, 50-100 times more potent than in activating the highly enriched and specific -sensitive adenylate cyclase of the firefly light organ. |
4(0,0,0,4) | Details |
| 976227 | Matsumura F, Beeman RW: Biochemical and physiological effects of chlordimeform. . Environ Health Perspect. 1976 Apr;14:71-82. In the American cockroach it directly stimulates the heart in situ, acts synergistically with in vivo, inhibits amine-N-acetyltransferase from cockroach head in vitro, causes accumulation of indolamines in cockroaches in vivo, and blocks the stimulation of adenylate cyclase by in the cockroach CNS in situ. |
1(0,0,0,1) | Details |
| 3927094 | Hashemzadeh H, Hollingworth RM, Voliva A: Receptors for 3H- in the adult firefly light organ. Life Sci. 1985 Aug 5;37(5):433-40. Competition studies with known octopaminergic agonists including the formamidine pesticides chlordimeform (CDM) and N-demethyl chlordimeform (DCDM) showed the following rank order of potencies in displacing DCDM greater than = synephrine greater than naphazoline greater than clonidine greater than CDM. These relative activities are similar to the abilities of the same compounds to alter adenylate cyclase activity in light organ homogenates. |
1(0,0,0,1) | Details |
| 6151458 | Morgan PJ, Mordue W: stimulates fluid secretion in locust malpighian tubules independently of cAMP. Comp Biochem Physiol C. 1984;79(2):305-10. Other biogenic amines, including synephrine and the formamidine chlordimeform were tested for their ability to stimulate fluid secretion. |
0(0,0,0,0) | Details |