| Name | SLOS |
|---|---|
| Synonyms | 7 DHC reductase; 7 dehydrocholesterol reductase; D7SR; DHCR 7; DHCR7; Putative sterol reductase SR 2; SLOS; Sterol delta 7 reductase… |
| Name | fenpropimorph |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 1958214 | Taton M, Rahier A: Identification of delta 5,7-sterol-delta 7-reductase in higher plant microsomes. Biochem Biophys Res Commun. 1991 Nov 27;181(1):465-73. The potent in vitro inhibition of the plant delta 5,7-sterol-delta 7-reductase by the ammonium-ion containing fungicides, tridemorph2 (3), fenpropimorph (4) and AY 9944 (5) was demonstrated. |
32(0,1,1,2) | Details |
| 11060346 | Ruan B, Tsai J, Wilson WK, Schroepfer GJ Jr: Aberrant pathways in the late stages of cholesterol biosynthesis in the rat. J Lipid Res. 2000 Nov;41(11):1772-82. Cholesta-5,8-dien-3beta-ol, its Delta (5,7) isomer, and other noncholesterol sterols accumulate in subjects with the Smith-Lemli-Opitz syndrome (SLOS), a severe developmental disorder caused by a defective Delta (7) sterol reductase gene. More than 60 different incubations were carried out with washed microsomes or the 10,000 g supernatant under aerobic or anaerobic conditions; some experiments included addition of cofactors, fenpropimorph (a Delta (8);-Delta (7) isomerase inhibitor), and/or AY-9944 (a Delta (7) reductase inhibitor). |
3(0,0,0,3) | Details |