Protein Information

Name quinone oxidoreductase
Synonyms Quinone oxidoreductase; Crystallin zeta; Zeta crystallin; Crystallin zetas; Quinone oxidoreductases; Zeta crystallins; CRYZ; Zeta crystalline…

Compound Information

Name fenpyroximate
CAS

Reference List

PubMed Abstract RScore(About this table)
12534287 Nakamaru-Ogiso E, Sakamoto K, Matsuno-Yagi A, Miyoshi H, Yagi T: The ND5 subunit was labeled by a photoaffinity analogue of fenpyroximate in bovine mitochondrial complex I. Biochemistry. 2003 Jan 28;42(3):746-54.

Fenpyroximate is a potent inhibitor of the mitochondrial proton-translocating NADH-quinone oxidoreductase (complex I).
81(1,1,1,1) Details
12914922 Nakamaru-Ogiso E, Seo BB, Yagi T, Matsuno-Yagi A: Amiloride inhibition of the proton-translocating NADH-quinone oxidoreductase of mammals and bacteria. FEBS Lett. 2003 Aug 14;549(1-3):43-6.

These results together with our earlier observation that the amiloride analogues prevent labeling of the ND5 subunit of complex I with a fenpyroximate analogue suggest the involvement of ND5 in H (+) (Na (+)) translocation and no direct involvement of electron carriers in H (+) (Na (+)) translocation.
2(0,0,0,2) Details