| Name | estrogen receptor |
|---|---|
| Synonyms | ER; ERA; ER alpha; ERalpha; ESR; ESR 1; ESR1; ESRA… |
| Name | fenvalerate |
|---|---|
| CAS | cyano(3-phenoxyphenyl)methyl 4-chloro-α-(1-methylethyl)benzeneacetate |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 16626760 | Lemaire G, Mnif W, Mauvais P, Balaguer P, Rahmani R: Activation of alpha- and beta-estrogen receptors by persistent pesticides in reporter cell lines. Life Sci. 2006 Aug 15;79(12):1160-9. Epub 2006 Mar 27. In our model, fifteen of the tested pesticides were found to agonize the ERalpha-mediated transcription in a dose-dependent manner and DDT, trans-nonachlor, chlordane, fenvalerate and toxaphene were also capable to activate ERbeta. |
86(1,1,1,6) | Details |
| 10966511 | Saito K, Tomigahara Y, Ohe N, Isobe N, Nakatsuka I, Kaneko H: Lack of significant estrogenic or antiestrogenic activity of pyrethroid insecticides in three in vitro assays based on classic estrogen receptor alpha-mediated mechanisms. Toxicol Sci. 2000 Sep;57(1):54-60. Estrogenic and antiestrogenic activity of pyrethroid insecticides (d-trans-allethrin, cypermethrin, empenthrin, fenvalerate, imiprothrin, permethrin, d-phenothrin and prallethrin) was evaluated using a suite of three in vitro assays based on classic human estrogen receptor alpha (hER alpha)-mediated mechanisms. |
32(0,1,1,2) | Details |
| 12396874 | Chen H, Xiao J, Hu G, Zhou J, Xiao H, Wang X: Estrogenicity of organophosphorus and pyrethroid pesticides. J Toxicol Environ Health A. 2002 Oct 11;65(19):1419-35. The present study was undertaken to evaluate the estrogenic activities of nine pesticides (phoxim, malathion, monocrotophos, dimethoate, opunal, fenvalerate, cypermethrin, permethrin, and deltamethrin) using three in vitro methods [E-Screen assay, estrogen receptor (ER) competitive binding assay, and pS2 expression assay]. |
31(0,1,1,1) | Details |
| 12052007 | Kunimatsu T, Yamada T, Ose K, Sunami O, Kamita Y, Okuno Y, Seki T, Nakatsuka I: Lack of (anti-) androgenic or estrogenic effects of three pyrethroids (esfenvalerate, fenvalerate, and permethrin) in the Hershberger and uterotrophic assays. Regul Toxicol Pharmacol. 2002 Apr;35(2 Pt 1):227-37. In the present study, we evaluated the interaction of three pyrethroids (esfenvalerate, fenvalerate, and permethrin) with androgen receptor (AR)- and estrogen receptor (ER)-mediated mechanisms using in vivo short-term assays. |
31(0,1,1,1) | Details |
| 15799245 | Chen R, Li A, Zhu T, Li C, Liu Q, Chang HC, Zhou J: JWA--a novel environmental-responsive gene, involved in estrogen receptor-associated signal pathway in MCF-7 and MDA-MB-231 breast carcinoma cells. J Toxicol Environ Health A. 2005 Mar 26;68(6):445-56. The pyrethroid insecticide fenvalerate and the organophosphorus insecticide phoxim are now the most widely used agents for indoor pest control in China. |
2(0,0,0,2) | Details |
| 15118252 | Kim IY, Shin JH, Kim HS, Lee SJ, Kang IH, Kim TS, Moon HJ, Choi KS, Moon A, Han SY: Assessing estrogenic activity of pyrethroid insecticides using in vitro combination assays. J Reprod Dev. 2004 Apr;50(2):245-55. In addition, we measured estrogen receptor (ER) protein and pS2 mRNA levels in human breast cancer cells (MCF-7 BUS) to clarify the mechanism of their estrogenicity. Seven pyrethroid insecticides (bioallethrine, cypermethrin, deltamethrin, fenvalerate, permethrin, sumithrin, and tetramethrin) were tested because of their worldwide usage. |
2(0,0,0,2) | Details |
| 20230880 | Gao X, Yu L, Castro L, Moore AB, Hermon T, Bortner C, Sifre M, Dixon D: An endocrine-disrupting chemical, fenvalerate, induces cell cycle progression and collagen type I expression in human uterine leiomyoma and myometrial cells. Toxicol Lett. 2010 Mar 15. Competitive binding assays revealed that the affinity of Fen binding to estrogen receptors (ERs) is non-detectable compared to E (2). |
1(0,0,0,1) | Details |