Protein Information

Name calcineurin inhibitors
Synonyms CABIN 1; CAIN; CABIN1; Calcineurin binding protein 1; Calcineurin binding protein cabin 1; Calcineurin inhibitor; Calcineurin binding protein 1s; Calcineurin binding protein cabin 1s…

Compound Information

Name fenvalerate
CAS cyano(3-phenoxyphenyl)methyl 4-chloro-α-(1-methylethyl)benzeneacetate

Reference List

PubMed Abstract RScore(About this table)
7531976 Richter A, Davies DE, Alexander P: Growth inhibitory effects of FK506 and cyclosporin A independent of inhibition of calcineurin. Biochem Pharmacol. 1995 Jan 31;49(3):367-73.

The role of calcineurin in CyA- or FK506-induced growth inhibition was investigated using the synthetic pyrethroid insecticides: cypermethrin, deltamethrin and fenvalerate, which are known calcineurin inhibitors.
31(0,1,1,1) Details
9070464 Victor RG, Rusnak F, Sikkink R, Marban E, O'Rourke B: Mechanism of Ca (2+)-dependent inactivation of L-type Ca2+ channels in GH3 cells: direct evidence against dephosphorylation by calcineurin. J Membr Biol. 1997 Mar 1;156(1):53-61.


Similarly, blocking calmodulin activation with calmidazolium or blocking calcineurin with fenvalerate did not influence the extent of Ca (2+)-dependent inactivation after photolysis.
0(0,0,0,0) Details