Name | Acetylcholinesterase |
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Synonyms | ACHE; ACHE protein; AChE; ARACHE; AcChoEase; Acetylcholine acetylhydrolase; Acetylcholinesterase; Acetylcholinesterase isoform E4 E6 variant… |
Name | fenvalerate |
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CAS | cyano(3-phenoxyphenyl)methyl 4-chloro-α-(1-methylethyl)benzeneacetate |
PubMed | Abstract | RScore(About this table) | |
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10355540 | Kale M, Rathore N, John S, Bhatnagar D: Lipid peroxidative damage on pyrethroid exposure and alterations in antioxidant status in rat erythrocytes: a possible involvement of reactive species. Toxicol Lett. 1999 Apr 12;105(3):197-205. A single dose of cypermethrin and/or fenvalerate (0.001% LD50) was administered orally to rats and the animals were sacrificed at 0, 1, 3, 7 and 14 days of treatment. Erythrocytes and serum acetylcholinesterase (AChE) activity was measured in pyrethroid-induced oxidative stress as it may mimic inhibition in target tissues such as muscle and brain. |
3(0,0,0,3) | Details |
15178118 | Eder KJ, Leutenegger CM, Wilson BW, Werner I: Molecular and cellular biomarker responses to pesticide exposure in juvenile chinook salmon (Oncorhynchus tshawytscha). Mar Environ Res. 2004 Aug-Dec;58(2-5):809-13. Four to five month old salmon were exposed to a range of pesticide concentrations, and tissue samples of surviving fish were analyzed for stress protein expression, cytokine transcription, and acetylcholinesterase (AChE) activity. |
2(0,0,0,2) | Details |
15171950 | Srinivas R, Udikeri SS, Jayalakshmi SK, Sreeramulu K: Identification of factors responsible for insecticide resistance in Helicoverpa armigera. Comp Biochem Physiol C Toxicol Pharmacol. 2004 Mar;137(3):261-9. Moth larvae (Helicoverpa armigera Hubner) collected from field crops were tested for resistance to cypermethrin, fenvalerate, endosulfan, monocrotophos and quinolphos. Acetylcholinesterase of resistant larvae was less sensitive to monocrotophos and methyl paraoxon. |
2(0,0,0,2) | Details |
8739525 | Mandal TK, Chakraborty AK, Bhattacharya A, Ghosh RK, Majumder S: The disposition kinetics and residues of fenvalerate in tissues following a single dermal application to black Bengal goats. Vet Res Commun. 1996;20(3):265-72. Serum acetylcholinesterase activities were increased after 24 h but were below the initial values from 48 to 120 h. |
1(0,0,0,1) | Details |
15454122 | Garg UK, Pal AK, Jha GJ, Jadhao SB: Haemato-biochemical and immuno-pathophysiological effects of chronic toxicity with synthetic pyrethroid, organophosphate and chlorinated pesticides in broiler chicks. Int Immunopharmacol. 2004 Dec 15;4(13):1709-22. Haemato- biochemical and immuno-pathophysiological changes following feeding of broiler chicks with 20 ppm fenvalerate (synthetic pyrethroid, SP), 2 ppm monocrotophos (organophosphate, OP) and 2 ppm endosulfan (chlorinated hydrocarbon, CH) were studied. |
0(0,0,0,0) | Details |
12558165 | Denton DL, Wheelock CE, Murray SA, Deanovic LA, Hammock BD, Hinton DE: Joint acute toxicity of esfenvalerate and diazinon to larval fathead minnows (Pimephales promelas). Environ Toxicol Chem. 2003 Feb;22(2):336-41. After pesticide exposures, larvae were evaluated for carboxylesterase and acetylcholinesterase activity, and histopathological effects. |
1(0,0,0,1) | Details |
19778241 | David M, Patil VK, Chebbi SG, Marigoudar SR, Chittaragi JB, Halappa R: Gas-liquid chromatography for fenvalerate residue analysis: in vivo alterations in the acetylcholinesterase activity and in different tissues of the fish, Labeo rohita (Hamilton). Toxicol Mech Methods. 2009 Sep;19(6-7):410-5. L. rohita on exposure to lethal (6 microg/L) and sub-lethal (0.75 microg/L) concentrations of fenvalerate showed time- and dose-dependent inhibition in the activity of AChE, suggesting a decrease in the cholinergic transmission and consequent accumulation of in the tissues (brain, gill, liver, and muscle) leading to continuous nerve impulses, causing prolonged muscle contraction which, as a consequence, causes paralysis and results in death. |
94(1,1,3,4) | Details |
2365420 | Ansari MZ, Kumar A, Prasad RL, Basu A, Sahai BN, Sinha AP: Clinico-biochemical use of serum acetylcholine esterase following treatment with synthetic pyrethroids, cypermethrin and fenvalerate, in cattle and buffalo experimentally infested with Boophilus microplus. Indian J Exp Biol. 1990 Mar;28(3):241-4. Following treatment, cypermethrin and fenvalerate, were found to have inhibitory effect on serum acetylcholine esterase (AchE) activity of cattle and buffalo experimentally infested with B. microplus. |
87(1,1,2,2) | Details |
15248660 | Tilak KS, Veeraiah K, Sastry LV, Rao JV: Effect of fenvalerate technical grade on acetyl cholinesterase activity in Indian bullfrog Haplobatrachus tigerinus (Daudin). J Environ Biol. 2003 Oct;24(4):445-8. The AChE activity was inhibited in first three hours of administration of fenvalerate in all the tissue tested. |
81(1,1,1,1) | Details |
8385837 | Malaviya M, Husain R, Seth PK, Husain R: Perinatal effects of two pyrethroid insecticides on brain neurotransmitter function in the neonatal rat. Vet Hum Toxicol. 1993 Apr;35(2):119-22. These pups also showed a significant decrease in the activity of brain monoamine oxidase and Na+, K (+)-ATPase and a significant increase in acetylcholinesterase from gestational exposure to fenvalerate. |
12(0,0,2,2) | Details |
9315226 | Majumder S, Chakraborty AK, Bhattacharyya A, Mandal TK, Basak DK: Effect of short-term dermal toxicity of fenvalerate on residue, cell architecture and biochemical profiles in broiler chicks. Indian J Exp Biol. 1997 Feb;35(2):162-7. Fenvalerate (0.1%) increased the aspartate aminotransferase (AST) (except brain), alanine aminotransferase (ALT), alkaline phosphatase (AP), acid phosphatase (AcP) (only brain) activities, level (only liver) in liver, kidney, heart and brain tissues; and 1% increased the AST (except brain), ALT, AcP (except liver and kidney), AP (only heart), (only liver) and decreased AP (except heart), AcP (only kidney), (except liver and heart), and acetylcholinesterase (AChE) (liver and brain) of liver, kidney, heart and brain tissue homogenates respectively. |
6(0,0,1,1) | Details |
1833318 | Rao KV, Ghouselazam S, Surendranath P: Inhibition and recovery of selected target enzyme activities in tissues of penaeid prawn, Metapenaeus monoceros (Fabricius), exposed to different insecticides. Indian J Exp Biol. 1991 May;29(5):489-91. The target enzymes, acetylcholinesterase (for phosphamidon and carbaryl) and Mg2+ ATPase (for DDT and fenvalerate) have been assayed during exposure and reclamation of these insecticides in M. monoceros. |
31(0,1,1,1) | Details |
12020021 | Wang KY, Liu TX, Yu CH, Jiang XY, Yi MQ: Resistance of aphis gossypii (Homoptera: Aphididae) to fenvalerate and imidacloprid and activities of detoxification enzymes on cotton and cucumber. J Econ Entomol. 2002 Apr;95(2):407-13. Activities of acetylcholinesterase (AChE) and alpha-naphthylacetate (alpha-NA) esterases of A. gossypii were significantly different among the three strains, with the R-fenvalerate strains having the highest, followed by the R-imidacloprid strain, and the S strain the lowest. |
7(0,0,1,2) | Details |
15186033 | el-Demerdash FM, Yousef MI, Kedwany FS, Baghdadi HH: Role of fenvalerate-induced changes in oxidative stress, hemato-biochemical parameters, and semen quality of male rats. J Environ Sci Health B. 2004 May;39(3):443-59. The activity of acetylcholinesterase was significantly (P < 0.05) decreased in brain and plasma, while plasma urea, and concentrations were significantly (P < 0.05) increased in rats treated with fenvalerate. |
and in ameliorating the 6(0,0,1,1) | Details |
1581676 | Reddy PM, Philip GH, Bashamohideen M: Regulation of AChE system of freshwater fish, Cyprinus carpio, under fenvalerate toxicity. Bull Environ Contam Toxicol. 1992 Jan;48(1):18-22. |
6(0,0,1,1) | Details |
17421051 | Wu G, Miyata T, Kang CY, Xie LH: Insecticide toxicity and synergism by enzyme inhibitors in 18 species of pest insect and natural enemies in crucifer vegetable crops. Pest Manag Sci. 2007 May;63(5):500-10. Meanwhile, the inhibitory effects of these enzyme inhibitors on the activities of acetylcholinesterases (AChE), carboxyesterases (CarE) and glutathione-S-transferases (GST), in vivo, were also studied. PB showed the highest synergism on methamidophos, fenvalerate, fipronil and avermectin in nine species of pest insects and natural enemies. |
3(0,0,0,3) | Details |
16011852 | Wheelock CE, Eder KJ, Werner I, Huang H, Jones PD, Brammell BF, Elskus AA, Hammock BD: Individual variability in esterase activity and CYP1A levels in Chinook salmon (Oncorhynchus tshawytscha) exposed to esfenvalerate and chlorpyrifos. Aquat Toxicol. 2005 Aug 30;74(2):172-92. Acetylcholinesterase (AChE) activity has traditionally been monitored as a biomarker of organophosphate (OP) and/or exposure. |
3(0,0,0,3) | Details |