Protein Information

Name HAMP
Synonyms HAMP; HEPC; HFE2B; Hepcidin; Hepcidin antimicrobial peptide; Hepcidin precursor; LEAP 1; LEAP1…

Compound Information

Name fludioxonil
CAS

Reference List

PubMed Abstract RScore(About this table)
19011080 Dongo A, Bataille-Simoneau N, Campion C, Guillemette T, Hamon B, Iacomi-Vasilescu B, Katz L, Simoneau P: The group III two-component histidine kinase of filamentous fungi is involved in the fungicidal activity of the bacterial polyketide ambruticin. Appl Environ Microbiol. 2009 Jan;75(1):127-34. Epub 2008 Nov 14.

Disruption of the osmosensor group III histidine kinase gene AbNIK1 (for A. brassicola NIK1) resulted in high levels of resistance to ambruticin and fludioxonil, while a mutant isolate characterized by a single-amino-acid substitution in the HAMP domain of the kinase only exhibited moderate resistance.
31(0,1,1,1) Details