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Radice S, Ferraris M, Marabini L, Grande S, Chiesara E: Effect of iprodione, a dicarboximide fungicide, on primary cultured rainbow trout (Oncorhynchus mykiss) hepatocytes. Aquat Toxicol. 2001 Sep;54(1-2):51-8.
Moreover, our experiments also demonstrate that iprodione is able to induce "in vitro" CYP1A1, leading to the conclusion that the production of ROS is due to this phenomenon. |
31(0,1,1,1) |
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16696176 |
Washington T, Tchounwou PB: Cytotoxicity and transcriptional activation of stress genes in human liver carcinoma (HepG2) cells exposed to iprodione. Int J Environ Res Public Health. 2004 Mar;1(1):12-20.
At 250 ug/mL exposure, the induction levels were 1.2 +/- 0.4, 50.1 +/- 17.8, 3.9 +/- 1.2, 16.8 +/- 7.2, 10.7 +/- 0.7, 1.8 +/- 0, 26.3 +/- 10.0, 7.2 +/- 2.4, 1.8 +/- 0.0, 6.8 +/- 1.3, 6.7 +/- 0.5, and 4.3 +/- 1.8 for CYP1A1, GSTYa, XRE, HMTIIA, c-fos, NF-kBRE, HSP70, CRE, RARE, GADD153, GADD45, and GRP78, respectively. |
1(0,0,0,1) |
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