Protein Information

Name CYP1A1
Synonyms AHH; AHRR; Arylhydrocarbon hydroxylase; CP11; CYP 1; CYP1; CYP1A1; CYPIA 1…

Compound Information

Name iprodione
CAS

Reference List

PubMed Abstract RScore(About this table)
11451425 Radice S, Ferraris M, Marabini L, Grande S, Chiesara E: Effect of iprodione, a dicarboximide fungicide, on primary cultured rainbow trout (Oncorhynchus mykiss) hepatocytes. Aquat Toxicol. 2001 Sep;54(1-2):51-8.

Moreover, our experiments also demonstrate that iprodione is able to induce "in vitro" CYP1A1, leading to the conclusion that the production of ROS is due to this phenomenon.
31(0,1,1,1) Details
16696176 Washington T, Tchounwou PB: Cytotoxicity and transcriptional activation of stress genes in human liver carcinoma (HepG2) cells exposed to iprodione. Int J Environ Res Public Health. 2004 Mar;1(1):12-20.

At 250 ug/mL exposure, the induction levels were 1.2 +/- 0.4, 50.1 +/- 17.8, 3.9 +/- 1.2, 16.8 +/- 7.2, 10.7 +/- 0.7, 1.8 +/- 0, 26.3 +/- 10.0, 7.2 +/- 2.4, 1.8 +/- 0.0, 6.8 +/- 1.3, 6.7 +/- 0.5, and 4.3 +/- 1.8 for CYP1A1, GSTYa, XRE, HMTIIA, c-fos, NF-kBRE, HSP70, CRE, RARE, GADD153, GADD45, and GRP78, respectively.
1(0,0,0,1) Details