| Name | cytochrome P450 (protein family or complex) |
|---|---|
| Synonyms | cytochrome P450; cytochrome P 450; CYP450; CYP 450 |
| Name | isoproturon |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 12226498 | Didierjean L, Gondet L, Perkins R, Lau SM, Schaller H, O'Keefe DP, Werck-Reichhart D: Engineering herbicide metabolism in tobacco and Arabidopsis with CYP76B1, a cytochrome P450 enzyme from Jerusalem artichoke. Plant Physiol. 2002 Sep;130(1):179-89. Transformation with CYP76B1 conferred on tobacco and Arabidopsis a 20-fold increase in tolerance to linuron, a compound detoxified by a single dealkylation, and a 10-fold increase in tolerance to isoproturon or chlortoluron, which need successive catalytic steps for detoxification. |
2(0,0,0,2) | Details |
| 2979785 | Schoket B, Zilahy Z, Molnar J, Vincze I: Comparative investigation of antipyrine half-life and induction of cytochrome P-450 dependent monooxygenases in rats treated with phenylurea herbicides. In Vivo. 1987 May-Jun;1(3):185-7. Isoproturon was ineffective, while chlortoluron and diuron decreased the half-life significantly. |
2(0,0,0,2) | Details |
| 15769155 | De Prado JL, Osuna MD, Heredia A, De Prado R: Lolium rigidum, a pool of resistance mechanisms to ACCase inhibitor herbicides. J Agric Food Chem. 2005 Mar 23;53(6):2185-91. Three diclofop-methyl (DM) resistant biotypes of Lolium rigidum (R1, R2, and R3) were found in different winter wheat fields in Spain, continuously treated with DM, DM + chlortoluron, or DM + isoproturon. In biotype R2, which exhibited a medium level of resistance, there was an increased rate of oxidation of the aryl ring of diclofop, a reaction most likely catalyzed by a cytochrome P450 enzyme. |
1(0,0,0,1) | Details |
| 20183062 | Abass K, Turpeinen M, Pelkonen O: An evaluation of the cytochrome P450 inhibition potential of selected pesticides in human hepatic microsomes. J Environ Sci Health B. 2009 Aug;44(6):553-63. With the exceptions of alpha-cypermethrin, cypermethrin, isoproturon, carbaryl and abamectin, most pesticides inhibited relatively potently at least one CYP-selective activity, which may have relevance for potential interactions in occupational exposures and for further studies on the CYP-associated metabolism of respective pesticides. |
1(0,0,0,1) | Details |
| 12297088 | Greulich K, Hoque E, Pflugmacher S: Uptake, metabolism, and effects on detoxication enzymes of isoproturon in spawn and tadpoles of amphibians. Ecotoxicol Environ Saf. 2002 Jul;52(3):256-66. In vivo metabolism of ring-14C-labeled IPU by the cytochrome P-450 system was analyzed in tadpoles. |
1(0,0,0,1) | Details |