Protein Information

Name cytochrome P450 (protein family or complex)
Synonyms cytochrome P450; cytochrome P 450; CYP450; CYP 450

Compound Information

Name methomyl
CAS

Reference List

PubMed Abstract RScore(About this table)
20040949 Patil JA, Patil AJ, Sontakke AV, Govindwar SP: Effect of methomyl on hepatic mixed function oxidases in rats. Indian J Pharmacol. 2008 Aug;40(4):158-63.

RESULTS: Intraperitoneal administration of methomyl (4 mg/kg body weight) showed significant decrease in the level of cytochrome P (450) , and the activities of aminopyrine N-demethylase and aniline hydroxylase on the third day of the treatment.
13(0,0,2,3) Details
2869902 Christian MF, Yu SJ: Cytochrome P-450-dependent monooxygenase activity in the velvetbean caterpillar, Anticarsia gemmatalis Hubner. Comp Biochem Physiol C. 1986;83(1):23-7.

Piperonyl butoxide decreased and increased the toxicity of methomyl and methyl parathion, respectively, suggesting that the monooxygenase system of velvetbean caterpillars plays a major role in the detoxification of xenobiotics.
1(0,0,0,1) Details
11886776 Tsagkarakou A, Pasteur N, Cuany A, Chevillon C, Navajas M: Mechanisms of resistance to organophosphates in Tetranychus urticae (Acari: Tetranychidae) from Greece. Insect Biochem Mol Biol. 2002 Apr;32(4):417-24.


We investigated the mechanisms conferring resistance to methyl-parathion (44-fold) and to methomyl (8-fold) in Tetranychus urticae from Greece by studying the effect of synergists on the resistance and the kinetic characteristics of various enzymes in a resistant strain (RLAB) and a susceptible reference strain (SAMB).
0(0,0,0,0) Details