| Name | cytochrome P450 (protein family or complex) |
|---|---|
| Synonyms | cytochrome P450; cytochrome P 450; CYP450; CYP 450 |
| Name | flurprimidol |
|---|---|
| CAS | α-(1-methylethyl)-α-[4-(trifluoromethoxy)phenyl]-5-pyrimidinemethanol |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 15012200 | Rademacher W: GROWTH RETARDANTS: Effects on Biosynthesis and Other Metabolic Pathways. Annu Rev Plant Physiol Plant Mol Biol. 2000 Jun;51:501-531. To date, four different types of such inhibitors are known: (a) Onium compounds, such as chlormequat mepiquat chlorphonium, and AMO-1618, which block the cyclases copalyl- synthase and ent-kaurene synthase involved in the early steps of GA metabolism. (b) Compounds with an N-containing heterocycle, e.g. ancymidol, flurprimidol, tetcyclacis, paclobutrazol, uniconazole-P, and inabenfide. These retardants block cytochrome P450-dependent monooxygenases, thereby inhibiting oxidation of ent-kaurene into ent-kaurenoic acid. (c) Structural mimics of which is the co-substrate of dioxygenases that catalyze late steps of GA formation. |
1(0,0,0,1) | Details |
| 12231743 | Jennings JC, Coolbaugh RC, Nakata DA, West CA: Characterization and Solubilization of Kaurenoic Acid Hydroxylase from Gibberella fujikuroi. Plant Physiol. 1993 Mar;101(3):925-930. and the salts of several monovalent cations stimulated the conversion of ent-kaurenoic acid to these products, whereas CO and a number of known inhibitors of cytochrome P-450-dependent reactions, including paclobutrazol, tetcyclacis, BAS 111.W, flurprimidol, triarimol, and 1-phenylimida-zole, significantly reduced kaurenoic acid hydroxylase activity. |
32(0,1,1,2) | Details |