PubMed |
Abstract |
RScore(About this table) |
17705656 |
Nillos MG, Rodriguez-Fuentes G, Gan J, Schlenk D: Enantioselective acetylcholinesterase inhibition of the organophosphorous insecticides profenofos, fonofos, and crotoxyphos. Environ Toxicol Chem. 2007 Sep;26(9):1949-54.
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197(2,3,3,7) |
Details |
10732982 |
Hirashima A, Kuwano E, Eto M: Docking study of enantiomeric fonofos oxon bound to the active site of Torpedo californica acetylcholinesterase. Bioorg Med Chem. 2000 Mar;8(3):653-6.
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193(2,3,3,3) |
Details |
1581539 |
Maxwell DM, Brecht KM: Quantitative structure-activity analysis of acetylcholinesterase inhibition by oxono and thiono analogues of organophosphorus compounds. Chem Res Toxicol. 1992 Jan-Feb;5(1):66-71.
A comparison of the bimolecular rate constants (ki) for inhibition of electric eel acetylcholinesterase (AChE) by the oxono (i.e., P=O) and thiono (i.e., P=S) analogues of parathion, methylparathion, leptophos, fonofos, sarin, and soman revealed that the oxono/thiono ratios of ki values varied from 14 for soman to 1240 for parathion. |
35(0,1,1,5) |
Details |
3983973 |
Levi PE, Hodgson E: Oxidation of pesticides by purified cytochrome P-450 isozymes from mouse liver. Toxicol Lett. 1985 Feb-Mar;24(2-3):221-8.
The pesticides parathion, fonofos, DEF, Mocap and profenofos were oxidized by the reconstituted monooxygenase system to form acetylcholinesterase (AChE) inhibitors. |
31(0,1,1,1) |
Details |
2417385 |
Cohen SD, Williams RA, Killinger JM, Freudenthal RI: Comparative sensitivity of bovine and rodent acetylcholinesterase to in vitro inhibition by organophosphate insecticides. Toxicol Appl Pharmacol. 1985 Dec;81(3 Pt 1):452-9.
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11(0,0,0,11) |
Details |