Protein Information

Name AP 1 (protein family or complex)
Synonyms AP 1; AP 1 complex; AP1; Adapter related protein complex 1

Compound Information

Name benzalkonium chloride
CAS quaternary ammonium compounds, alkylbenzyldimethyl, chlorides

Reference List

PubMed Abstract RScore(About this table)
11099643 Xu KP, Li XF, Yu FS: Corneal organ culture model for assessing epithelial responses to surfactants. Toxicol Sci. 2000 Dec;58(2):306-14.

The effects of two surfactants, sodium dodecyl sulfate (SDS) and benzalkonium chloride (BAK), on corneal epithelial permeability and DNA-binding activity of AP-1 and NF-kappaB were studied in cultured bovine corneas.
82(1,1,1,2) Details
17881916 Okada Y: Effects of topical antiglaucoma medications on corneal epithelium as evaluated by gene expression patterns. Cornea. 2007 Oct;26(9 Suppl 1):S46-54.

PURPOSE: To examine the expression pattern of the stress-related genes c-fos and c-jun, which encode the 2 major components of activator protein (AP)-1, and cyclooxygenase (COX)-2 in rat corneal epithelium treated with topical antiglaucoma medications and benzalkonium chloride (BAK) preservative.
31(0,1,1,1) Details