| Name | bradykinin |
|---|---|
| Synonyms | Alpha 2 thiol proteinase inhibitor; BDK; Bradykinin; KNG; KNG 1; KNG1; Kininogen; Kininogen 1 precursor… |
| Name | benzalkonium chloride |
|---|---|
| CAS | quaternary ammonium compounds, alkylbenzyldimethyl, chlorides |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 1701214 | Bueb JL, Mousli M, Bronner C, Rouot B, Landry Y: Activation of Gi-like proteins, a receptor-independent effect of kinins in mast cells. Mol Pharmacol. 1990 Dec;38(6):816-22. The peptide hormones bradykinin and kallidin -bradykinin), as well as their analogues [des-Arg9]-bradykinin, a selective B1 agonist, [des-Arg9,Leu8]-bradykinin, a selective B1 antagonist, and [Thi5,8,D-Phe7]-bradykinin and D-Arg0-[Hyp3,D-Phe7]-bradykinin, two selective B2 antagonists, induced rapid release from purified rat peritoneal mast cells. The inhibitory effect of benzalkonium chloride showed that the G proteins involved belong to the Gi type. |
4(0,0,0,4) | Details |
| 8742508 | Niitsuma A, Uchida MK, Suzuki-Nishimura T: Benzalkonium chloride inhibited the release from rat peritoneal mast cells induced by bradykinin and oligomer-specific lectin Datura stramonium agglutinin, but did not. Gen Pharmacol. 1996 Jan;27(1):123-8. |
162(2,2,2,2) | Details |
| 6174350 | Kurose M, Saeki K: release induced by neurotensin from rat peritoneal mast cells. . Eur J Pharmacol. 1981 Dec 3;76(2-3):129-36. The effect of neurotensin was markedly different from that of substance P, bradykinin and compound 48/80 with respect to both the dose-response curve and the sensitivity to benzalkonium chloride. |
6(0,0,1,1) | Details |
| 1695472 | Bueb JL, Mousli M, Landry Y, Bronner C: A pertussis toxin-sensitive G protein is required to induce release from rat peritoneal mast cells by bradykinin. Agents Actions. 1990 Apr;30(1-2):98-101. release was dose-dependently inhibited by pertussis toxin (1-100 ng/ml) and by benzalkonium chloride (0.1-3 micrograms/ml). |
2(0,0,0,2) | Details |
| 92563 | Read GW, Kiefer EF: Benzalkonium chloride: selective inhibitor of release induced by compound 48/80 and other polyamines. J Pharmacol Exp Ther. 1979 Dec;211(3):711-5. |
0(0,0,0,0) | Details |
| 20162407 | Kaur R, O'Shaughnessy CT, Jarvie EM, Winchester WJ, McLean PG: Characterization of a calcitonin gene-related peptide release assay in rat isolated distal colon. Arch Pharm Res. 2009 Dec;32(12):1775-81. Epub 2010 Feb 17. The mast cell degranulator, compound 48/80 significantly increased CGRP release an effect that was blocked in the presence of the mast cell stabilizer, ketotifen and the selective Gi inhibitor benzalkonium chloride. |
0(0,0,0,0) | Details |