Protein Information

Name endothelin 1
Synonyms EDN 1; EDN1; ET1; Endothelin 1; Endothelin 1 precursor; PPET 1; PPET1; Preproendothelin 1…

Compound Information

Name benzalkonium chloride
CAS quaternary ammonium compounds, alkylbenzyldimethyl, chlorides

Reference List

PubMed Abstract RScore(About this table)
15279725 Wu KY, Wang HZ, Hong SJ: Inhibition of endothelin-1 and KCL-induced increase of [CA2+] i by antiglaucoma drugs in cultured A7r5 vascular smooth-muscle cells. J Ocul Pharmacol Ther. 2004 Jun;20(3):201-9.

The purpose of this study was to investigate the inhibitory effects of various commercial antiglaucoma drugs including brimonidine, dipivefrin, betaxolol, timolol, levobunolol, carteolol, brinzolamide, dorzolamide, unoprostone, latanoprost, pilocarpine, and preservative benzalkonium chloride on endothelin-1 (ET-1) and KCl-induced increase of intracellular free Ca2+ ([Ca2+] i) in cultured rat A7r5 vascular smooth muscle cells.
32(0,1,1,2) Details