Protein Information

Name catalase
Synonyms CAT; Catalase; Erythrocyte derived growth promoting factor; Carnitine O acetyltransferase; Carnitine acetylase; Carnitine acetyltransferase; CAT; Catalases…

Compound Information

Name gibberellic acid
CAS (1α,2β,4aα,4bβ,10β)-2,4a,7-trihydroxy-1-methyl-8-methylenegibb-3-ene-1,10-dicarboxylic acid 1,4a-lactone

Reference List

PubMed Abstract RScore(About this table)
15139192 Shi M, Cheng R: [Effects of zinc and boron nutrition on balsam pear (Momordica charantia) yield and quality, and polyamines, hormone, and senescence of its leaves]. Ying Yong Sheng Tai Xue Bao. 2004 Jan;15(1):77-80.

The reason was that Zn and B could increase polyamines (PAs), putrescine (Put), spermidine (Spd), spermine (Spm), indole acetic acid (IAA), gibberellic acid (GA3) and ascorbic acid (ASA) contents and superoxide dismutase (SOD), peroxidase (POD) and catalase (CAT) activities, and reduce malondialdehyde (MDA), abscisic acid (ABA) contents in leaves, which inhibited membrane lipid peroxidation.
31(0,1,1,1) Details
18020698 Lopez ML, Peralta-Videa JR, Castillo-Michel H, Martinez-Martinez A, Duarte-Gardea M, Gardea-Torresdey JL: Lead toxicity in alfalfa plants exposed to phytohormones and ethylenediaminetetraacetic acid monitored by peroxidase, catalase, and amylase activities. Environ Toxicol Chem. 2007 Dec;26(12):2717-23.

This manuscript describes the toxicity of lead in alfalfa plants treated with ethylenediaminetetraacetic acid (EDTA) and the phytohormones indole-3-acetic-acid (IAA), gibberellic acid (GA), and kinetin (KN), on catalase (CAT), ascorbate peroxidase (APOX), and total amylase activity (TAA).
7(0,0,1,2) Details
17518349 Celik I, Tuluce Y, Isik I: Evalution of toxicity of abcisic acid and gibberellic acid in rats: 50 days drinking water study. J Enzyme Inhib Med Chem. 2007 Apr;22(2):219-26.

In the present study, the influence of subchronic effects of two plant growth regulators (PGRs) [Abcisic acid (ABA) and Gibberellic acid (GA3)] on antioxidant defense systems [reduced glutathione (GSH), glutathione reductase (GR), superoxide dismutase (SOD), glutathione-S-transferase (GST) and catalase (CAT)] and lipid peroxidation level (malondialdehyde = MDA) in various tissues of the rat were investigated during treatment as a drinking water model. 75 ppm of ABA and GA3 in drinking water were continuously administered orally to rats (Sprague-Dawley albino) ad libitum for 50 days.
6(0,0,1,1) Details
19068651 Chen L, Song YF, Zhang W, Li XY, Wang L, Ji PH, Yang XX: [Assessment of toxicity effects for cadmium contamination in soils by means of multi-indexes]. Huan Jing Ke Xue. 2008 Sep;29(9):2606-12.

The genetic and eco-toxic effects of Cd (0-10 mg x kg (-1)) were studied with Vicia faba (broad bean) as the test species using meadow brown soil in pot experiments by means of several indexes, such as Vicia faba root tip micronucleus frequency (MCN), mitosis index (MI), and chromosomal aberrations frequency (CAF), antioxidant enzymes superoxide dismutases (SOD), peroxidases (POD), catalase (CAT) and phytohormone abscisic acid (ABA), gibberellic acid (GA3) and zeatin and zeatin riboside (Z&ZR;).
6(0,0,1,1) Details
17418944 Celik I, Turker M, Tuluce Y: Abcisic acid and gibberellic acid cause increased lipid peroxidation and fluctuated antioxidant defense systems of various tissues in rats. J Hazard Mater. 2007 Sep 30;148(3):623-9. Epub 2007 Mar 12.

The study was aimed at demonstrating changes in the antioxidant defense systems [Reduced glutathione (GSH), glutathione reductase (GR), superoxide dismutase (SOD), glutathione-S-transferase (GST) and catalase (CAT)] forming an antioxidative barrier and oxidative stress parameter (Malondialdehyde=MDA) in the various tissues of Sprague-Dawley rats which were administrated plant growth regulators (PGRs) [Abcisic acid (ABA) and Gibberellic acid (GA (3))] during 25 days.
6(0,0,1,1) Details
14193417 MAGDON E: [STUDIES ON THE EFFECT OF GIBBERELLIC ACID ON THE CATALASE ACTIVITY AND RADIOSENSITIVITY OF BIOLOGICAL SYSTEMS.] Radiobiol Radiother. 1964;5:243-7.
6(0,0,1,1) Details
14607525 Palma K, Kermode AR: Metabolism of hydrogen peroxide during reserve mobilization and programmed cell death of barley (Hordeum vulgare L.) aleurone layer cells. Free Radic Biol Med. 2003 Nov 15;35(10):1261-70.

During germination, aleurone layer cells of barley (Hordeum vulgare) grains synthesize and secrete hydrolytic enzymes (principally alpha-amylase) in response to gibberellic acid (GA); shortly thereafter, the aleurone layer cells undergo programmed death.
Gluconeogenesis of lipid reserves within aleurone cells, which supports this hydrolytic enzyme synthesis, results in the generation of H (2) O (2), which is catabolized by glyoxysomal catalase.
5(0,0,0,5) Details
6321215 Kumar KB, Khan PA: Age-related changes in catalase and peroxidase activities in the excised leaves of Eleusine coracana Gaertin. cv PR 202 during senescence. Exp Gerontol. 1983;18(5):409-17.

Both indoleacetic acid and gibberellic acid had no effect on the changes of chlorophyll but increased peroxidase activity.
4(0,0,0,4) Details
16660470 Evensen KB, Loy JB: Effects of Gibberellic Acid and Gold Light on Germination, Enzyme Activities, and Amino Acid Pool Size in a Dwarf Strain of Watermelon. Plant Physiol. 1978 Jul;62(1):6-9.

Osmotic inhibition of germination with mannitol in light-grown seeds of WB-2 was only slightly reversed by GA (3) at the concentrations used, whereas, GA (3) substantially relieved osmotic inhibition in dark-grown seeds.The effects of GA (3) and gold light on development of catalase and invertase activities and on levels of free amino acids in germinating seeds of WB-2 were examined.
2(0,0,0,2) Details
12114563 Hsieh TH, Lee JT, Yang PT, Chiu LH, Charng YY, Wang YC, Chan MT: Heterology expression of the Arabidopsis C-repeat/dehydration response element binding factor 1 gene confers elevated tolerance to chilling and oxidative stresses in transgenic tomato. Plant Physiol. 2002 Jul;129(3):1086-94.

The transgenic tomato plants exhibited patterns of growth retardation; however, they resumed normal growth after GA (3) (gibberellic acid) treatment.
The CAT1 gene and catalase activity were also highly induced in the transgenic tomato plants.
1(0,0,0,1) Details
12376629 Hsieh TH, Lee JT, Charng YY, Chan MT: Tomato plants ectopically expressing Arabidopsis CBF1 show enhanced resistance to water deficit stress. Plant Physiol. 2002 Oct;130(2):618-26.

Exogenous gibberellic acid treatment reversed the growth retardation and enhanced growth of transgenic tomato plants, but did not affect the level of water deficit resistance.
Catalase activity increased, and hydrogen peroxide concentration decreased in transgenic tomato plants compared with the wild-type plants with or without water deficit stress.
1(0,0,0,1) Details
16154987 Mitrovic A, Ducic T, Liric-Rajlic I, Radotic K, Zivanovic B: Changes in Chenopodium rubrum seeds with aging. Ann N Y Acad Sci. 2005 Jun;1048:505-8.

Peroxidase, superoxide dismutase, and catalase activity, as well as glutathione status, were determined in 2.5-h imbibed seeds.
Gibberellic acid reduced the difference in growth and flowering between plants derived from seeds different in age.
1(0,0,0,1) Details
11997375 Fath A, Bethke P, Beligni V, Jones R: Active oxygen and cell death in cereal aleurone cells. J Exp Bot. 2002 May;53(372):1273-82.

The cereal aleurone layer is a secretory tissue whose function is regulated by gibberellic acid (GA) and abscisic acid (ABA).
The sensitivity of GA-treated aleurone to light and H (2) O (2) is a result of lowered amounts of enzymes that metabolize AOS. mRNAs encoding catalase, ascorbate peroxidase and superoxide dismutase are all reduced during 6-18 h of incubation in GA, but these mRNAs were present in higher amounts in cells incubated in ABA.
1(0,0,0,1) Details
19815399 Troudi A, Mahjoubi Samet A, Zeghal N: Hepatotoxicity induced by gibberellic acid in adult rats and their progeny. Exp Toxicol Pathol. 2009 Oct 6.

Hepatotoxicity was objectified by the significant increase of malondialdehyde (MDA) level and a decrease of antioxidant enzyme activities such as catalase (CAT), superoxide dismutase (SOD), glutathione peroxidase (GPx) and glutathione content in liver of suckling pups and their mothers.
1(0,0,0,1) Details
11351079 Fath A, Bethke PC, Jones RL: Enzymes that scavenge reactive oxygen species are down-regulated prior to gibberellic acid-induced programmed cell death in barley aleurone. Plant Physiol. 2001 May;126(1):156-66.

The amounts and activities of ROS scavenging enzymes, including catalase (CAT), ascorbate peroxidase, and superoxide dismutase are strongly down-regulated in aleurone layers treated with GA.
1(0,0,0,1) Details
19619070 Muthuraman P, Srikumar K: A comparative study on the effect of homobrassinolide and gibberellic acid on lipid peroxidation and antioxidant status in normal and diabetic rats. J Enzyme Inhib Med Chem. 2009 Oct;24(5):1122-7.

Normal and diabetic rats (Albino -wistar strain) were administered 50 microg HB and GBA intradermally each day for seven days and their tissue and blood levels of malondialdehyde (MDA), 4-hydroxy-2-nonenol (4-HNE), reduced glutathione (GSH) content and catalase (CAT) activity were determined.
1(0,0,0,1) Details
2102847 Huang N, Sutliff TD, Litts JC, Rodriguez RL: Classification and characterization of the rice alpha-amylase multigene family. Plant Mol Biol. 1990 May;14(5):655-68.

The former sequence may be specific to alpha-amylase gene while the latter sequence may be related to a 'CATC' box found in many plant genes.
Another sequence called the pyrimidine box (TCCTTTTTC) was found in the alpha-amylase genes as well as other genes regulated by gibberellic acid (GA).
1(0,0,0,1) Details