Protein Information

Name protein is
Synonyms ANX 2; p36; LIP 2; LIP2; ANX2; ANX2L4; ANX2P1; ANX2P2…

Compound Information

Name gibberellic acid
CAS (1α,2β,4aα,4bβ,10β)-2,4a,7-trihydroxy-1-methyl-8-methylenegibb-3-ene-1,10-dicarboxylic acid 1,4a-lactone

Reference List

PubMed Abstract RScore(About this table)
8177211 Taylor BH, Scheuring CF: A molecular marker for lateral root initiation: the RSI-1 gene of tomato (Lycopersicon esculentum Mill) is activated in early lateral root primordia. Mol Gen Genet. 1994 Apr;243(2):148-57.

The predicted RSI-1 protein is rich in cysteine, lysine and proline, and includes an N-terminal region with characteristics of a signal peptide.
The putative mature protein exhibits 79% amino acid identity to a protein encoded by a gene (GAST1) that is induced by gibberellic acid in tomato shoots.
1(0,0,0,1) Details
18250077 Bassel GW, Mullen RT, Bewley JD: Procera is a putative DELLA mutant in tomato (Solanum lycopersicum): effects on the seed and vegetative plant. J Exp Bot. 2008;59(3):585-93. Epub 2008 Feb 3.

The procera (pro) mutant of tomato exhibits a well-characterized constitutive gibberellic acid (GA) response phenotype.
Transient expression of a LeGAI-GFP (green fluorescent protein) fusion protein in onion epidermis results in its location to the nucleus, and this protein is rapidly degraded by the proteasome in the presence of GA.
1(0,0,0,1) Details
1827067 Bartels D, Engelhardt K, Roncarati R, Schneider K, Rotter M, Salamini F: An ABA and GA modulated gene expressed in the barley embryo encodes an aldose reductase related protein. EMBO J. 1991 May;10(5):1037-43.

This first aldose reductase gene of plants is expressed constitutively during embryo maturation and is modulated by the plant hormones abscisic acid (ABA) and gibberellic acid (GA).
Immunohistochemistry showed that the protein is preferentially expressed in tissues formed at early stages in embryogenesis.
1(0,0,0,1) Details
16384900 Bethke PC, Hwang YS, Zhu T, Jones RL: Global patterns of gene expression in the aleurone of wild-type and dwarf1 mutant rice. Plant Physiol. 2006 Feb;140(2):484-98. Epub 2005 Dec 29.


The d1 protein is the sole alpha-subunit of heterotrimeric G-proteins in rice.
1(0,0,0,1) Details
20061304 Kato M, Nagasaki-Takeuchi N, Ide Y, Maeshima M: An arabidopsis hydrophilic Ca2 (+) -binding protein with a PEVK-rich domain, PCaP2, is associated with the plasma membrane and interacts with calmodulin and phosphatidylinositol phosphates. Plant Cell Physiol. 2010 Mar;51(3):366-79. Epub 2010 Jan 7.

The protein is rich in proline, glutamate, valine and lysine residues (PEVK-rich domain), and bound Ca (2+) even in the presence of Mg (2+) and K (+) when examined by the (45) Ca overlay assay.
Treatment of seedlings with K (+), Mn (2+), Zn (2+), Na (+), ABA and gibberellic acid, and cold and drought stresses enhanced the transcription.
1(0,0,0,1) Details
19689802 Hammond RW, Zhao Y: Modification of tobacco plant development by sense and antisense expression of the tomato viroid-induced AGC VIIIa protein kinase PKV suggests involvement in gibberellin signaling. BMC Plant Biol. 2009 Aug 18;9:108.

CONCLUSION: We have found that the over expression of the tomato protein kinase PKV resulted in stunting, modified vascular tissue development, reduced root formation, and male sterility in tobacco, and we propose that PKV regulates plant development by functioning in critical signaling pathways involved in gibberellic acid metabolism.
The encoded protein, PKV, is a novel member of the AGC VIIIa group of signal-transducing protein kinases; however, the role of PKV in plant development is unknown.
1(0,0,0,1) Details
9008387 Libal-Weksler Y, Vishnevetsky M, Ovadis M, Vainstein A: Isolation and regulation of accumulation of a minor chromoplast-specific protein from cucumber corollas. Plant Physiol. 1997 Jan;113(1):59-63.

Immunological characterization revealed that the protein is chromoplast-specific and that its steady-state level in corollas increases in parallel to flower development.
Gibberellic acid rapidly enhanced, whereas paclobutrazol down-regulated, the steady-state level of CHRD.
1(0,0,0,1) Details
16844903 Ham BK, Park JM, Lee SB, Kim MJ, Lee IJ, Kim KJ, Kwon CS, Paek KH: Tobacco Tsip1, a DnaJ-type Zn finger protein, is recruited to and potentiates Tsi1-mediated transcriptional activation. Plant Cell. 2006 Aug;18(8):2005-20. Epub 2006 Jul 14.

The transcript level of Tsip1 in tobacco (Nicotiana tabacum) increased upon treatment with salicylic acid (SA), ethylene, gibberellic acid, NaCl, and virus challenge.
1(0,0,0,1) Details
9435140 Shintani A, Kato H, Minamikawa T: Hormonal regulation of expression of two cysteine endopeptidase genes in rice seedlings. Plant Cell Physiol. 1997 Nov;38(11):1242-8.

The pRP60 protein is a major rice cysteine endopeptidase named REP-1 that digests rice glutelin, the main seed storage protein.
When seeds were de-embryonated and incubated, the amounts of both mRNAs were reduced to very low levels, but in the presence of 0.01 to 1 microM gibberellic acid (GA3) both again reached high levels.
1(0,0,0,1) Details
18987212 Xin Z, Wang A, Yang G, Gao P, Zheng ZL: The Arabidopsis A4 subfamily of lectin receptor kinases negatively regulates abscisic acid response in seed germination. Plant Physiol. 2009 Jan;149(1):434-44. Epub 2008 Nov 5.


Furthermore, LecRKA4.2 suppression by RNA interference in lecrka4.1-1 showed stronger ABA inhibition of seed germination than lecrka4.1-1, while the response to gibberellic acid was not affected in lecrka4.1-1 and lecrka4.1-1; LecRKA4.2 (RNAi) lines.
0(0,0,0,0) Details
17264065 Ide Y, Nagasaki N, Tomioka R, Suito M, Kamiya T, Maeshima M: Molecular properties of a novel, hydrophilic cation-binding protein associated with the plasma membrane. J Exp Bot. 2007;58(5):1173-83. Epub 2007 Jan 29.


On the other hand, other sugars, abscisic acid, gibberellic acid, dehydration, and low temperature had little or no effect on PCaP1 transcript abundance.
0(0,0,0,0) Details
9312067 Vishnevetsky M, Ovadis M, Itzhaki H, Vainstein A: CHRC, encoding a chromoplast-specific carotenoid-associated protein, is an early gibberellic acid-responsive gene. J Biol Chem. 1997 Oct 3;272(40):24747-50.
7(0,0,1,2) Details
13677467 Furtado A, Henry R, Scott K, Meech S: The promoter of the asi gene directs expression in the maternal tissues of the seed in transgenic barley. Plant Mol Biol. 2003 Jul;52(4):787-99.

Expression in maternal rather than endosperm tissues of the grain suggests that earlier widespread assumptions that the protein is expressed largely in the endosperm may have been largely based on analysis of mixed grain tissues.
The expression of the asi gene that encodes BASI has been reported to be controlled by the hormones abscisic acid (ABA) and gibberellic acid (GA).
1(0,0,0,1) Details
18941053 Piskurewicz U, Jikumaru Y, Kinoshita N, Nambara E, Kamiya Y, Lopez-Molina L: The gibberellic acid signaling repressor RGL2 inhibits Arabidopsis seed germination by stimulating abscisic acid synthesis and ABI5 activity. Plant Cell. 2008 Oct;20(10):2729-45. Epub 2008 Oct 21.

Increased ABI5 protein is ultimately responsible for preventing seed germination when GA levels are reduced.
1(0,0,0,1) Details
1495490 Casacuberta JM, Raventos D, Puigdomenech P, San Segundo B: Expression of the gene encoding the PR-like protein PRms in germinating maize embryos. Mol Gen Genet. 1992 Jul;234(1):97-104.

The PRms protein is a pathogenesis-related (PR)-like protein whose mRNA accumulates during germination of maize seeds.
To further our investigations on the expression of the PRms gene we examined the accumulation of PRms mRNA in different tissues of maize seedlings infected with F. moniliforme and studied the effect of fungal elicitors, the mycotoxin moniliformin, the hormone gibberellic acid, and specific chemical agents.
1(0,0,0,1) Details