Protein Information

Name Acetylcholinesterase
Synonyms ACHE; ACHE protein; AChE; ARACHE; AcChoEase; Acetylcholine acetylhydrolase; Acetylcholinesterase; Acetylcholinesterase isoform E4 E6 variant…

Compound Information

Name heptenophos
CAS 7-chlorobicyclo[3.2.0]hepta-2,6-dien-6-yl dimethyl phosphate

Reference List

PubMed Abstract RScore(About this table)
8783813 Worek F, Kirchner T, Backer M, Szinicz L: Reactivation by various oximes of human erythrocyte acetylcholinesterase inhibited by different organophosphorus compounds. Arch Toxicol. 1996;70(8):497-503.

For this purpose human erythrocyte AChE (EC 3.1.1.7) was inhibited (30 min) by chlorfenvinphos, dichlorvos, dicrotophos, heptenophos, mevinphos, monocrotophos, paraoxon, phosphamidon, trichlorfon, malaoxon, omethoate, oxydemeton-methyl or methamidophos by 85-98% of control.
84(1,1,1,4) Details
15679473 Antonijevic B, Bokonjic D, Stojiljkovic MP, Kilibarda V, Milovanovic ZA, Nedeljkovic M, Maksimovic M: Efficacy of trimedoxime in mice poisoned with dichlorvos, heptenophos or monocrotophos. Basic Clin Pharmacol Toxicol. 2005 Feb;96(2):111-7.

Administration of the oxime produced a significant reactivation of central and peripheral acetylcholinesterase inhibited with dichlorvos and heptenophos, with the exception of erythrocyte acetylcholinesterase inhibited by heptenophos.
82(1,1,1,2) Details
2539961 Besser R, Hopf HC, Gutmann L, Dillmann U: [The decrement-increment phenomenon in disorders of neuromuscular transmission by inhibition of acetylcholinesterase]. EEG EMG Z Elektroenzephalogr Elektromyogr Verwandte Geb. 1989 Mar;20(1):28-33.

1(0,0,0,1) Details
1632947 Skladal P, Mascini M: Sensitive detection of pesticides using amperometric sensors based on cobalt phthalocyanine-modified composite electrodes and immobilized cholinesterases. Biosens Bioelectron. 1992;7(5):335-43.

The determination of organophosphate and carbamate pesticides was carried out using cobalt phthalocyanine-modified carbon epoxy composite electrodes coupled with acetylcholinesterase or butyrylcholinesterase.
With this approach, 1.5 and 8.4 micrograms l-1 of paraoxon and heptenophos, respectively, can be detected in less than 3 min.
1(0,0,0,1) Details
2841086 Besser R, Dillmann U, Gutmann L, Hopf HC: [The repetitive muscular action potential in neuromuscular transmission disorders due to acetylcholinesterase inhibition]. EEG EMG Z Elektroenzephalogr Elektromyogr Verwandte Geb. 1988 Jun;19(2):85-91.

1(0,0,0,1) Details
18969806 Solna R, Sapelnikova S, Skladal P, Winther-Nielsen M, Carlsson C, Emneus J, Ruzgas T: Multienzyme electrochemical array sensor for determination of phenols and pesticides. Talanta. 2005 Jan 30;65(2):349-57.

The screen-printed four-electrode system was used as the amperometric transducer for determination of phenols and pesticides using immobilised tyrosinase, peroxidase, acetylcholinesterase and butyrylcholinesterase.
The detection of p-cresol, catechol and phenol as well as of pesticides including carbaryl, heptenophos and fenitrothion was carried out in flow-through and steady state arrangements.
1(0,0,0,1) Details