Protein Information

Name P2X7
Synonyms ATP receptor; Purinergic receptor; P2RX7; P2X purinoceptor 7; P2X7; P2Z receptor; Purinoceptor P2X7; P2X purinoceptor 7s…

Compound Information

Name benzalkonium chloride
CAS quaternary ammonium compounds, alkylbenzyldimethyl, chlorides

Reference List

PubMed Abstract RScore(About this table)
18490962 Dutot M, Liang H, Pauloin T, Brignole-Baudouin F, Baudouin C, Warnet JM, Rat P: Effects of toxic cellular stresses and divalent cations on the human P2X7 cell death receptor. Mol Vis. 2008 May 19;14:889-97.

Different specific stresses were then induced by a chemical toxin (benzalkonium chloride) and a chemical oxidant (tert-butyl hydroperoxide) to assess the role of the P2X7 receptor.
44(0,1,2,9) Details
16799018 Dutot M, Pouzaud F, Larosche I, Brignole-Baudouin F, Warnet JM, Rat P: Fluoroquinolone eye drop-induced cytotoxicity: role of preservative in P2X7 cell death receptor activation and apoptosis. Invest Ophthalmol Vis Sci. 2006 Jul;47(7):2812-9.

METHODS: Corneal and conjunctival cell lines were incubated with preserved (benzalkonium chloride [BAC]) or unpreserved ofloxacin solutions for 15 minutes.
4(0,0,0,4) Details