Protein Information

Name lipase
Synonyms HGL; HPL; HGL; Human giant larvae homolog; LGL 2; LGL2; LLGL 2; LLGL2…

Compound Information

Name octhilinone
CAS

Reference List

PubMed Abstract RScore(About this table)
19486005 King AR, Lodola A, Carmi C, Fu J, Mor M, Piomelli D: A critical cysteine residue in monoacylglycerol lipase is targeted by a new class of isothiazolinone-based enzyme inhibitors. Br J Pharmacol. 2009 Jul;157(6):974-83. Epub 2009 May 26.

KEY RESULTS: The screening revealed that 2-octyl-4-isothiazolin-3-one (octhilinone) inhibited purified rat recombinant MGL (IC (50)= 88 +/- 12 nM) through a partially reversible mechanism.
2(0,0,0,2) Details