| Name | protoporphyrinogen oxidase |
|---|---|
| Synonyms | Mutant protoporphyrinogen oxidase; VP; PPO; PPOX; Protoporphyrinogen oxidase; V290M; Protoporphyrinogen oxidases |
| Name | oxadiazon |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 2522396 | Matringe M, Camadro JM, Labbe P, Scalla R: Protoporphyrinogen oxidase inhibition by three peroxidizing herbicides: oxadiazon, LS 82-556 and M&B; 39279. FEBS Lett. 1989 Mar 13;245(1-2):35-8. |
112(1,2,2,2) | Details |
| 16506820 | Aliferis KA, Chrysayi-Tokousbalides M: Metabonomic strategy for the investigation of the mode of action of the phytotoxin (5S,8R,13S,16R)-(-)-pyrenophorol using 1H nuclear magnetic resonance fingerprinting. J Agric Food Chem. 2006 Mar 8;54(5):1687-92. Analysis results revealed that none of the herbicide treatments fitted the pyrenophorol model and indicate that the effect of the phytotoxin on A. sterilis differs than those caused by mesotrione, norflurazon, oxadiazon, paraquat, and diuron, which inhibit 5-enolpyruvylshikimate-3- synthase, 4-hydroxyphenyl--dioxygenase, desaturase, protoporphyrinogen oxidase, photosystem I, and photosystem II, respectively. |
81(1,1,1,1) | Details |
| 8621563 | Camadro JM, Labbe P: Cloning and characterization of the yeast HEM14 gene coding for protoporphyrinogen oxidase, the molecular target of diphenyl ether-type herbicides. J Biol Chem. 1996 Apr 12;271(15):9120-8. |
4(0,0,0,4) | Details |
| 8653563 | Krijt J, Maruna P, Petrovicky P, Janousek V: The effect of protoporphyrinogen oxidase inhibitors on microsomal and mitochondrial cytochromes. Obes Res. 1995 Dec;3 Suppl 5:785S-788S. In a separate experiment, male ICR mice were fed 1000 ppm of the oxidaseinhibiting herbicide oxadiazon in the diet for 10 days. |
3(0,0,0,3) | Details |
| 11517729 | Warabi E, Usui K, Tanaka Y, Matsumoto H: Resistance of a soybean cell line to oxyfluorfen by overproduction of mitochondrial protoporphyrinogen oxidase. Pest Manag Sci. 2001 Aug;57(8):743-8. The growth of resistant cells was also insensitive to oxadiazon [5-tert-butyl-3-(2,4-dichloro-5-isopropoxyphenyl)-1,3,4-oxadiazol-2-(3H)- one], the other chemical class of Protox inhibitor. |
2(0,0,0,2) | Details |
| 11368593 | Dayan FE, Meazza G, Bettarini F, Signorini E, Piccardi P, Romagni JG, Duke SO: Synthesis, herbicidal activity, and mode of action of IR 5790. J Agric Food Chem. 2001 May;49(5):2302-7. IR 5790, an arylthiadiazolone herbicide structurally related to oxadiargyl and oxadiazon, was synthesized. The phenotypic responses of susceptible plants, such as interruption of growth and light-dependent development of necrotic areas on the foliage, are consistent with those observed with protoporphyrinogen oxidase-inhibiting herbicides. |
2(0,0,0,2) | Details |
| 11484905 | Krijt J, Krijtova H, Sanitrak J: Effect of tiagabine and on metabolism in an in vivo model of porphyria. Pharmacol Toxicol. 2001 Jul;89(1):15-22. Administration of the protoporphyrinogen oxidase inhibitor oxadiazon (12.5 mg/kg/day) for four days to male Wistar rats caused a partial block of biosynthesis, thus mimicking the condition of quiescent variegate porphyria. |
31(0,1,1,1) | Details |
| 2146157 | Varsano R, Matringe M, Magnin N, Mornet R, Scalla R: Competitive interaction of three peroxidizing herbicides with the binding of [3H] acifluorfen to corn etioplast membranes. FEBS Lett. 1990 Oct 15;272(1-2):106-8. The specific binding of the herbicide acifluorfen 5-[2-chloro-4-(trifluoromethyl) phenoxy]-2-nitrobenzoic acid to corn etioplast membranes is competitively inhibited by the substrate of protoporphyrinogen oxidase. Three other peroxidizing molecules, oxadiazon [5-terbutyl-3-(2,4-dichloro-5-isopropoxyphenyl)-1,3,4-oxadiazol -2-one], LS 82556 [(S) 3-N-(methylbenzyl) carbamoyl-5-propionyl-2,6-lutidine], and M&B; 39279 [5-amino-4-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl) pyrazol], also compete with acifluorfen for its binding site. |
2(0,0,0,2) | Details |
| 9431441 | Krijt J, Stranska P, Maruna P, Vokurka M, Sanitrak J: Herbicide-induced experimental variegate porphyria in mice: tissue porphyrinogen accumulation and response to porphyrogenic drugs. Can J Physiol Pharmacol. 1997 Oct-Nov;75(10-11):1181-7. Administration of oxadiazon or oxyfluorfen (1000 ppm in the diet) to male BALB/c mice for 9 days resulted in experimental porphyria, resembling the acute phase of human variegate porphyria. Both herbicides caused a decrease of protoporphyrinogen oxidase activity in liver and kidney. |
1(0,0,0,1) | Details |