Name | ubiquitin |
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Synonyms | HMG20; RPS27A; UBA80; UBCEP 1; UBCEP1; UBA52; UBCEP 2; UBCEP2… |
Name | TCA |
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CAS | 2,2,2-trichloroacetic acid |
PubMed | Abstract | RScore(About this table) | |
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17241446 | Shlevin L, Regev-Rudzki N, Karniely S, Pines O: Location-specific depletion of a dual-localized protein. Traffic. 2007 Feb;8(2):169-76. The depletion of the protein occurs post-translationally via degradation by the ubiquitin-proteasome system, which operates only in the cytosol and the nucleus. |
3(0,0,0,3) | Details |
17101781 | Pan Y, Mansfield KD, Bertozzi CC, Rudenko V, Chan DA, Giaccia AJ, Simon MC: Multiple factors affecting cellular redox status and energy metabolism modulate hypoxia-inducible factor prolyl hydroxylase activity in vivo and in vitro. Mol Cell Biol. 2007 Feb;27(3):912-25. Epub 2006 Nov 13. Prolyl hydroxylation of hypoxible-inducible factor alpha (HIF-alpha) proteins is essential for their recognition by pVHL containing ubiquitin ligase complexes and subsequent degradation in (O (2))-replete cells. |
1(0,0,0,1) | Details |
15917633 | Carlson E, Bays N, David L, Skach WR: Reticulocyte lysate as a model system to study endoplasmic reticulum membrane protein degradation. Methods Mol Biol. 2005;301:185-205. These substrates can be rapidly isolated in native ER membranes which, when incubated in RRL lacking exogenous hemin, are degraded in an ATP-dependent manner by the ubiquitin-proteasome pathway. |
1(0,0,0,1) | Details |