Protein Information

Name enolase
Synonyms 2 phospho D glycerate hydrolyase; T suppressor LYMPHOKINE; 2 phospho D glycerate hydro lyase; Enolase; Beta enolase; ENO 3; ENO3; Enolase 3…

Compound Information

Name TCA
CAS 2,2,2-trichloroacetic acid

Reference List

PubMed Abstract RScore(About this table)
16962558 Brandina I, Graham J, Lemaitre-Guillier C, Entelis N, Krasheninnikov I, Sweetlove L, Tarassov I, Martin RP: Enolase takes part in a macromolecular complex associated to mitochondria in yeast. Biochim Biophys Acta. 2006 Sep-Oct;1757(9-10):1217-28. Epub 2006 Jul 12.

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17258477 Kim Y, Nandakumar MP, Marten MR: Proteome map of Aspergillus nidulans during osmoadaptation. Fungal Genet Biol. 2007 Sep;44(9):886-95. Epub 2007 Jan 26.


Sequence homology and conserved domains were used to assign probable function to twenty-one proteins currently annotated as "hypothetical." In osmoadapted cells, there was an increased expression of glyceraldehyde-3-phosphate dehydrogenase and aldehyde dehydrogenase, as well as a decreased expression of enolase, suggesting an increased glycerol biosynthesis and decreased use of the TCA cycle.
1(0,0,0,1) Details
17339216 Hynes MJ, Szewczyk E, Murray SL, Suzuki Y, Davis MA, Sealy-Lewis HM: Transcriptional control of gluconeogenesis in Aspergillus nidulans. Genetics. 2007 May;176(1):139-50. Epub 2007 Mar 4.


Cloning of acuN has shown that it encodes enolase, an enzyme involved in both glycolysis and gluconeogenesis.
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15690349 Wittmann C, Hans M, van Winden WA, Ras C, Heijnen JJ: Dynamics of intracellular metabolites of glycolysis and TCA cycle during cell-cycle-related oscillation in Saccharomyces cerevisiae. Biotechnol Bioeng. 2005 Mar 30;89(7):839-47.


Minor differences resulted for phosphoglucose isomerase and enolase.
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