Protein Information

Name choline acetyltransferase
Synonyms CHAT; CHOACTase; CLAT; CMS1A; CMS1A2; ChAT; Choline O acetyltransferase; Choline acetylase…

Compound Information

Name benzalkonium chloride
CAS quaternary ammonium compounds, alkylbenzyldimethyl, chlorides

Reference List

PubMed Abstract RScore(About this table)
3792770 Dahl JL, Bloom DD, Epstein ML, Fox DA, Bass P: Effect of chemical ablation of myenteric neurons on neurotransmitter levels in the rat jejunum. Gastroenterology. 1987 Feb;92(2):338-44.

Within 2 days after benzalkonium chloride treatment, there was a 40% reduction in the activity of choline acetyltransferase, a specific marker for cholinergic neurons, and a 25% reduction in the amount of vasoactive intestinal peptide per centimeter length of jejunum.
81(1,1,1,1) Details
19100458 Dong YL, Liu W, Gao YM, Wu RD, Zhang YH, Wang HF, Wei B: Neural stem cell transplantation rescues rectum function in the aganglionic rat. Transplant Proc. 2008 Dec;40(10):3646-52.

MATERIALS AND METHODS: Rat central nervous system-derived NSCs (CNS-NSCs) obtained from the cortex of the fetal brain (E16) were transplanted into the benzalkonium chloride (BAC)-induced rat aganglionic rectum.
The protein expression of neuronal nitric oxide synthase (nNOS) and choline acetyltransferase (ChAT) were significantly increased and the RAIR restored after cell implantation.
1(0,0,0,1) Details