Name | hexosaminidase |
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Synonyms | Beta N acetylhexosaminidase; Beta hexosaminidase A; Beta hexosaminidase alpha chain; Beta hexosaminidase alpha chain precursor; HEXA; HEXA protein; Hexosaminidase A; Hexosaminidase A preproprotein variant… |
Name | benzalkonium chloride |
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CAS | quaternary ammonium compounds, alkylbenzyldimethyl, chlorides |
PubMed | Abstract | RScore(About this table) | |
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1607234 | Williams DE, Nguyen KD, Shapourifar-Tehrani S, Kitada S, Lee DA: Effects of timolol, betaxolol, and levobunolol on human tenon's fibroblasts in tissue culture. Invest Ophthalmol Vis Sci. 1992 Jun;33(7):2233-41. To investigate this question further, the antiproliferative effects of the preservative benzalkonium chloride and three pure and commercially available beta-adrenergic antagonist preparations (timolol, betaxolol, and levobunolol) were studied on tissue cultures of human Tenon's capsule fibroblasts. Fibroblast growth was measured with tritiated uptake and hexosaminidase assays. |
1(0,0,0,1) | Details |
12130703 | Stenton GR, Nohara O, Dery RE, Vliagoftis H, Gilchrist M, Johri A, Wallace JL, Hollenberg MD, Moqbel R, Befus AD: Proteinase-activated receptor (PAR)-1 and -2 agonists induce mediator release from mast cells by pathways distinct from PAR-1 and PAR-2. J Pharmacol Exp Ther. 2002 Aug;302(2):466-74. Using benzalkonium chloride, which antagonizes the actions of 48/80 by competing for the same G (i) protein, we determined that benzalkonium chloride suppressed tc-LIGRLO-NH (2)-mediated (0.1 microM) beta-hexosaminidase release by 62%. |
34(0,1,1,4) | Details |