Protein Information

Name albumin
Synonyms ALB; Albumin; PRO0883; PRO0903; PRO1341; PRO1708; PRO2044; PRO2619…

Compound Information

Name benzalkonium chloride
CAS quaternary ammonium compounds, alkylbenzyldimethyl, chlorides

Reference List

PubMed Abstract RScore(About this table)
1424063 Imayasu M, Moriyama T, Ohashi J, Ichijima H, Cavanagh HD: A quantitative method for LDH, MDH and albumin levels in tears with ocular surface toxicity scored by Draize criteria in rabbit eyes. CLAO J. 1992 Oct;18(4):260-6.

Lesions were produced with solutions of 0.005-0.02% benzalkonium chloride (BAK), 0.01-0.03% chlorhexidine digluconate (CHX), and 0.01-0.03% polyhexamethylene biguanide hydrochloride (PHMB), all of which are widely used in topical ophthalmic preparations.
6(0,0,0,6) Details
18378229 Sanchis-Merino ME, Montero JA, Ruiz-Moreno JM, Rodriguez AE, Pastor S: Comparative efficacy of topical antihistamines in an animal model of early phase allergic conjunctivitis. Exp Eye Res. 2008 May;86(5):791-7. Epub 2008 Mar 4.

In order to compare the relative efficacy of topical antihistamines with balanced saline solution (BSS) and benzalkonium chloride (BC) in the early phase of allergic conjunctivitis in an animal model of ocular anaphylaxis, 96 male guinea pigs were sensitized with intraperitoneal egg albumin (EA) and aluminum hydroxide.
6(0,0,1,1) Details
10413874 Oie S, Kamiya A, Tomita M, Katayama A, Iwasaki A, Miyamura S: Efficacy of disinfectants and heat against Escherichia coli O157:H7. Microbios. 1999;98(389):7-14.

After exposure to 0.1% benzalkonium chloride, 0.1% chlorhexidine gluconate containing a nonionic surfactant, and 80% (v/v) ethanol, 99.99% of viable bacterial cells were killed at 20 degrees C within 15 s irrespective of the presence or absence of 0.1% albumin.
6(0,0,1,1) Details
15923059 Rabenau HF, Kampf G, Cinatl J, Doerr HW: Efficacy of various disinfectants against SARS coronavirus. J Hosp Infect. 2005 Oct;61(2):107-11.

Three surface disinfectants were investigated at 0.5% for 30 min and 60 min (Mikrobac forte, based on benzalkonium chloride and laurylamine; Kohrsolin FF, based on benzalkonium chloride, glutaraldehyde and didecyldimonium chloride; Dismozon pur, based on magnesium monoperphthalate), and one instrument disinfectant was investigated at 4% for 15 min, 3% for 30 min and 2% for 60 min [Korsolex basic, based on glutaraldehyde and (ethylenedioxy) dimethanol].
Three types of organic load were used: 0.3% albumin, 10% fetal calf serum, and 0.3% albumin with 0.3% sheep erythrocytes.
1(0,0,0,1) Details
1458577 Stone JA, Moriguchi JR, Notto DR, Murphy PE, Dass CJ, Wessels LM, Freier EF: Discrepancies between sodium concentrations measured by the Kodak Ektachem 700 and by dilutional and direct ion-selective electrode analyzers. Clin Chem. 1992 Dec;38(12):2419-22.


The differences do not appear to be related to any previously identified sources of discrepancy, such as variations in triglycerides, bicarbonate, total protein, albumin, or gamma-globulin, the presence of paraproteins, or interference by benzalkonium chloride from heparinized catheters.
0(0,0,0,0) Details