Name | glutathione reductase |
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Synonyms | GLUR; GR; GRD 1; GRD1; GRase; GSR; Glutathione reductase; GRases… |
Name | TCA |
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CAS | 2,2,2-trichloroacetic acid |
PubMed | Abstract | RScore(About this table) | |
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17999340 | Celik I, Isik I: Determination of chemopreventive role of Foeniculum vulgare and Salvia officinalis infusion on trichloroacetic acid-induced increased serum marker enzymes lipid peroxidation and antioxidative defense systems in rats. Nat Prod Res. 2008 Jan 10;22(1):66-75. The chemopreventive potential of the plant infusions were evaluated by measuring levels of serum marker enzymes [aspartate aminotransferase (AST), alanin aminotransferase (ALT), phosphokinase (CPK), acid phosphatase (ACP), alkaline phosphatase (ALP) and lactate dehydrogenase (LDH)], antioxidant defense systems (GSH), glutathione reductase (GR), superoxide dismutase (SOD), glutathione-S-transferase (GST) and catalase (CAT)] and lipid peroxidation level (Malondialdehyde = MDA) in various tissues of rats. |
1(0,0,0,1) | Details |
16849376 | Takahashi H, Hayashi M, Goto F, Sato S, Soga T, Nishioka T, Tomita M, Kawai-Yamada M, Uchimiya H: Evaluation of metabolic alteration in transgenic rice overexpressing dihydroflavonol-4-reductase. Ann Bot. 2006 Oct;98(4):819-25. Epub 2006 Jul 18. In YK1 calli, an approx. 3-fold increase in was observed, whereas the activities of peroxidase and glutathione reductase were concomitantly increased. |
1(0,0,0,1) | Details |
20199583 | Kamaraj S, Anandakumar P, Jagan S, Ramakrishnan G, Devaki T: lung carcinogenesis in mice. Fundam Clin Pharmacol. 2010 Feb 22. B (a) P (50 mg/kg body weight)-induced mitochondrial abnormalities was evident from alterations in mitochondrial lipid peroxides, antioxidant status (superoxide dismutase, catalase, peroxidase, glutathione reductase, glutathione-S-transferase, and major tricarboxylic acid (TCA) cycle enzyme activities (isocitrate dehydrogenase, succinate dehydrogenase, malate dehydrogenase, alpha-ketoglutarate dehydrogenase), electron transport chain (ETC) complexes activities and levels. |
attenuates mitochondrial dysfunction during benzo (a) pyrene-induced 1(0,0,0,1) | Details |
15881660 | Selvendiran K, Thirunavukkarasu C, Singh JP, Padmavathi R, Sakthisekaran D: Chemopreventive effect of piperine on mitochondrial TCA cycle and phase-I and metabolizing enzymes in benzo (a) pyrene induced lung carcinogenesis in Swiss albino mice. Mol Cell Biochem. 2005 Mar;271(1-2):101-6. The activities of -metabolizing enzymes peroxidase (GPx), glutathione reductase (GR) and -6-phospho dehydrogenase (G6PDH) were significantly lowered in lung-cancer bearing mice when compared with control mice. |
-1(0,0,0,1) | Details |
17622976 | Celik I, Tuluce Y: Elevation protective role of Camellia sinensis and Urtica dioica infusion against trichloroacetic acid-exposed in rats. Phytother Res. 2007 Nov;21(11):1039-44. The preventive potential of the plant infusions was evaluated by measuring the level of serum marker enzymes, aspartate aminotransferase (AST), alanine aminotransferase (ALT), phosphokinase (CPK), acid phosphatase (ACP), alkaline phosphatase (ALP) and lactate dehydrogenase (LDH); antioxidant defense systems, (GSH), glutathione reductase (GR), superoxide dismutase (SOD), glutathione-S-transferase (GST) and catalase (CAT); and lipid peroxidation (malondialdehyde, MDA) content in various organs of rats. |
1(0,0,0,1) | Details |
17349985 | Arulkumaran S, Ramprasath VR, Shanthi P, Sachdanandam P: Alteration of DMBA-induced oxidative stress by additive action of a modified indigenous preparation--Kalpaamruthaa. Chem Biol Interact. 2007 Apr 25;167(2):99-106. Epub 2007 Feb 4. The hepatic mitochondrial fraction of untreated DMBA rats showed 2.96-fold increase in MDA content when compared to control rats and abnormal changes in the activities/levels of mitochondrial enzymic (superoxide dismutase, peroxidase and glutathione reductase) and non-enzymic and antioxidants were observed. |
1(0,0,0,1) | Details |