| Name | CYP24A1 |
|---|---|
| Synonyms | 24 OHase; CP24; CYP24; CYP24A1; Cytochrome P450 Subfamily XXIV; Cytochrome P450 family 24 subfamily A polypeptide 1; P450 CC24; Vitamin D 24 hydroxylase… |
| Name | cycloheximide |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 18162528 | Shankar K, Liu X, Singhal R, Chen JR, Nagarajan S, Badger TM, Ronis MJ: Chronic consumption leads to disruption of homeostasis associated with induction of renal -24-hydroxylase (CYP24A1). Endocrinology. 2008 Apr;149(4):1748-56. Epub 2007 Dec 27. CYP24A1 mRNA induction in RPTCs was also inhibited by the protein synthesis inhibitor cycloheximide. |
89(1,1,1,9) | Details |
| 15538745 | Lou YR, Nazarova N, Talonpoika R, Tuohimaa P: inhibits 1alpha,25--induced expression of CYP24 in human prostate cancer cells. Prostate. 2005 May 15;63(3):222-30. |
1(0,0,0,1) | Details |
| 16371233 | Wu-Wong JR, Nakane M, Ma J: Effects of analogs on the expression of plasminogen activator inhibitor-1 in human vascular cells. Thromb Res. 2006;118(6):709-14. Epub 2005 Dec 20. The effect of paricalcitol on suppressing PAI-1 in SMC was blocked by cycloheximide, suggesting that protein synthesis was involved. As a comparison, SMC expressed VDR and paricalcitol induced CYP24A1 mRNA in SMC (> 150-fold at 10 nM) dose-dependently. |
1(0,0,0,1) | Details |
| 17159355 | Wu-Wong JR, Nakane M, Ma J: analogs modulate the expression of plasminogen activator inhibitor-1, thrombospondin-1 and thrombomodulin in human aortic smooth muscle cells. J Vasc Res. 2007;44(1):11-8. Epub 2006 Dec 7. The effect of paricalcitol on THBS1 in SMC was blocked by cycloheximide, while its effect on TM and CYP24A1 was not affected, suggesting that the regulation of THBS1 by VDR may be mediated through intermediate factors, but that TM is likely a direct target of VDR. |
0(0,0,0,0) | Details |