Protein Information

Name HSD11B
Synonyms 11 DH; 11 beta HSD1; 11 beta hydroxysteroid dehydrogenase 1; Corticosteroid 11 beta dehydrogenase isozyme 1; HDL; HSD11; HSD11B; HSD11B1…

Compound Information

Name cycloheximide
CAS

Reference List

PubMed Abstract RScore(About this table)
19109222 Lee HY, Acosta TJ, Skarzynski DJ, Okuda K: Prostaglandin F2alpha stimulates 11Beta-hydroxysteroid dehydrogenase 1 enzyme bioactivity and protein expression in bovine endometrial stromal cells. Biol Reprod. 2009 Apr;80(4):657-64. Epub 2008 Dec 23.

Cycloheximide, a general translational inhibitor, abolished the stimulatory effects of PGF2alpha on HSD11B1 protein expression in endometrial stromal cells, indicating that PGF2alpha increases HSD11B1 protein expression by stimulating a posttranscriptional process rather than a transcriptional mechanism.
85(1,1,1,5) Details