Protein Information

Name adipose differentiation related protein
Synonyms ADFP; ADPH; ADRP; Adipophilin; Adipose differentiation related protein; Adipophilins; Adipose differentiation related proteins

Compound Information

Name cycloheximide
CAS

Reference List

PubMed Abstract RScore(About this table)
18854426 Gu JQ, Ikuyama S, Wei P, Fan B, Oyama J, Inoguchi T, Nishimura J: Pycnogenol, an extract from French maritime pine, suppresses Toll-like receptor 4-mediated expression of adipose differentiation-related protein in macrophages. Am J Physiol Endocrinol Metab. 2008 Dec;295(6):E1390-400. Epub 2008 Oct 14.

Actinomycin D almost completely abolished the LPS effect, whereas cycloheximide decreased the expression at 12 h, indicating that the LPS-induced ADRP expression was stimulated at the transcriptional level and was also mediated by new protein synthesis.
40(0,1,1,10) Details
15731108 Wolins NE, Quaynor BK, Skinner JR, Schoenfish MJ, Tzekov A, Bickel PE: S3-12, Adipophilin, and TIP47 package lipid in adipocytes. . J Biol Chem. 2005 May 13;280(19):19146-55. Epub 2005 Feb 24.

Inhibition of protein synthesis with cycloheximide does not block the oleate-induced formation of the nascent lipid droplets, nor does it prevent TAG accumulation.
6(0,0,0,6) Details