Protein Information

Name CD95
Synonyms ALPS1A; APT1; FAS; APO 1; APO 1 cell surface antigen; APO1; Apo 1 Fas; Apo 1 antigen…

Compound Information

Name copper sulfate
CAS sulfuric acid copper(2+) salt (1:1)

Reference List

PubMed Abstract RScore(About this table)
12175101 Harada S, Sugiyama E, Taki H, Shinoda K, Fujita T, Maruyama M, Kobayashi M: D-penicillamine cooperates with copper sulfate to enhance the surface expression of functional Fas antigen in rheumatoid synovial fibroblasts via the generation of hydrogen peroxide. Clin Exp Rheumatol. 2002 Jul-Aug;20(4):469-76.

To determine whether this inhibitory action is involved in Fas-mediated apoptosis, we examined the effect of DP and copper sulfate on the expression and function of Fas antigen in rheumatoid synovial fibroblasts (RSFs).
127(1,2,4,7) Details
8628997 Pronk GJ, Ramer K, Amiri P, Williams LT: Requirement of an ICE-like protease for induction of apoptosis and ceramide generation by REAPER. Science. 1996 Feb 9;271(5250):808-10.


Thus, the intracellular RPR protein uses cell death signaling pathways similar to those used by the vertebrate transmembrane receptors Fas (CD95) and tumor necrosis factor receptor type 1.
1(0,0,0,1) Details