| Name | caspase 1 |
|---|---|
| Synonyms | CASP 1; p45; CASP1; CASP1 nirs variant 1; CASP1 protein; Caspase 1; Caspase 1 isoform alpha variant; Caspase 1 isoform zeta… |
| Name | cycloheximide |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 18497737 | He F, Doucet JA, Stephens JM: Caspase-mediated degradation of PPARgamma proteins in adipocytes. . Obesity (Silver Spring). 2008 Aug;16(8):1735-41. Epub 2008 May 22. Use of several specific caspase inhibitors revealed that caspase-1 was activated following treatment with TNFalpha and cycloheximide (CH), and inhibition of caspase-1 blocked the cleavage of PPARgamma proteins in cultured adipocytes. |
81(1,1,1,1) | Details |
| 15657078 | Depuydt B, van Loo G, Vandenabeele P, Declercq W: Induction of apoptosis by TNF receptor 2 in a T-cell hybridoma is FADD dependent and blocked by caspase-8 inhibitors. J Cell Sci. 2005 Feb 1;118(Pt 3):497-504. Epub 2005 Jan 18. We show here that TNFR2-mediated apoptosis in PVC60 cells can be blocked by the broad-spectrum caspase inhibitor zVAD-fmk, the caspase-8 inhibitor zIETD-fmk and by CrmA, a viral inhibitor of caspase-1 and caspase-8. |
1(0,0,0,1) | Details |
| 16215688 | Singh S, Khar A: Differential gene expression during apoptosis induced by a serum factor: role of mitochondrial F0-F1 ATP synthase complex. Apoptosis. 2005 Dec;10(6):1469-82. Caspase 1 and caspase 3 activity and the loss of mitochondrial membrane potential were also inhibited by oligomycin during apoptosis in these cells, suggesting that the oligomycin induced inhibition of apoptosis could be due to inhibition of caspase activity and inhibition of mitochondrial depolarization. |
1(0,0,0,1) | Details |
| 18493980 | Kang TJ, Basu S, Zhang L, Thomas KE, Vogel SN, Baillie L, Cross AS: Bacillus anthracis spores and lethal toxin induce IL-1beta via functionally distinct signaling pathways. Eur J Immunol. 2008 Jun;38(6):1574-84. Previous reports suggested that lethal toxin (LT)-induced caspase-1 activity and/or IL-1beta accounted for Bacillus anthracis (BA) infection lethality. |
3(0,0,0,3) | Details |