Name | glucose transporter 1 |
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Synonyms | Erythrocyte/hepatoma glucose transporter; GLUT; GLUT 1; GLUT1; Glucose transporter 1; HepG2 glucose transporter; SLC2A1; Glucose transporter 1s… |
Name | cycloheximide |
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CAS |
PubMed | Abstract | RScore(About this table) | |
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16051672 | Moeller LC, Dumitrescu AM, Refetoff S: Cytosolic action of thyroid hormone leads to induction of hypoxia-inducible factor-1alpha and glycolytic genes. Mol Endocrinol. 2005 Dec;19(12):2955-63. Epub 2005 Jul 28. Using microarrays and real-time PCR we found mRNAs of the following genes increased in response to T (3) in a TRbeta-specific manner: the transcription factor hypoxia-inducible factor (HIF)-1alpha, its target genes transporter (GLUT) 1 and platelet-type phosphofructokinase (PFKP), and the monocarboxylate transporter (MCT) 4. |
3(0,0,0,3) | Details |
18479958 | Lee MY, Han HJ: Galectin-1 upregulates glucose transporter-1 expression level via protein kinase C, phosphoinositol-3 kinase, and mammalian target of rapamycin pathways in mouse embryonic stem cells. Int J Biochem Cell Biol. 2008;40(11):2421-30. Epub 2008 Apr 6. Moreover, galectin-1 increased glucose transporter-1 mRNA and protein expression levels, which were inhibited by a disruption in transcription by actinomycin D and translation by the cycloheximide. |
34(0,1,1,4) | Details |
15547951 | Chiou GY, Fong JC: Synergistic effect of transport in 3T3-L1 adipocytes. J Cell Biochem. 2005 Feb 15;94(3):627-34. The synergistic effect of these two agents was suppressed in the presence of cycloheximide and actinomycin D. In concord, immunoblot and Northern blot analyses revealed that GLUT1 protein and mRNA levels were both increased in cells pretreated with both PGF2alpha and 8-bromo cAMP, greater than the additive effect of each agent alone. |
and cyclic AMP on 3(0,0,0,3) | Details |
17015939 | Purintrapiban J, Suttajit M, Forsberg NE: Differential activation of transport in cultured muscle cells by polyphenolic compounds from Canna indica L. Biol Pharm Bull. 2006 Oct;29(10):1995-8. The CI extract increased the amount of transporter isoforms 1 (GLUT1) and 4 (GLUT4) at the cell surface and enhanced expression of GLUT1 protein. Cycloheximide treatment almost completely reversed CI-induced 2-DG uptake to the basal level. |
2(0,0,0,2) | Details |
15946695 | Han HJ, Heo JS, Lee YJ: ANG II increases 2-deoxyglucose uptake in mouse embryonic stem cells. . Life Sci. 2005 Aug 26;77(15):1916-33. ANG II significantly increased cell proliferation and 2-DG uptake in concentration- and time-dependent manner (> 18 h, > 10 (-8) M) and increased mRNA and protein level of GLUT1 by 31+/-7% and 22+/-5% compared to control, respectively. Actinomycin D and cycloheximide completely blocked the effect of ANG II on 2-DG uptake. |
1(0,0,0,1) | Details |
15695798 | Paik JY, Lee KH, Ko BH, Choe YS, Choi Y, Kim BT: endothelial cells through increased hexokinase activity and GLUT1 expression. J Nucl Med. 2005 Feb;46(2):365-70. SNP-stimulated (18) F-FDG uptake was abolished by cotreatment with cycloheximide, the kinase inhibitor the phosphatidylinositol-3 kinase (PI3K) inhibitor wortmannin, or the protein kinase C inhibitor staurosporine. |
stimulates 18F-FDG uptake in human 3(0,0,0,3) | Details |
16543731 | Heo JS, Han HJ: PKC and MAPKs pathways mediate EGF-induced stimulation of 2-deoxyglucose uptake in mouse embryonic stem cells. Cell Physiol Biochem. 2006;17(3-4):145-58. Epub 2006 Mar 14. EGF significantly increased 2-DG uptake in time- and concentration- dependent manner (> 12 hr, > 10 ng/ ml) and increased mRNA and protein level of glucose transporter 1 (GLUT1) compared to control, respectively. Actinomycin D and cycloheximide completely blocked the effect of EGF on 2-DG uptake. |
1(0,0,0,1) | Details |