Protein Information

Name ATPases
Synonyms (NA+ + K+)ATPase; ATP1A1; ATPase; ATPase Na+/K+ transporting alpha 1 polypeptide; Na (+) K (+) ATPase; Na (+),K (+) ATPase; Na + K + ATPase; Na K + ATPase…

Compound Information

Name copper sulfate
CAS sulfuric acid copper(2+) salt (1:1)

Reference List

PubMed Abstract RScore(About this table)
8048974 Odermatt A, Suter H, Krapf R, Solioz M: Primary structure of two P-type ATPases involved in copper homeostasis in Enterococcus hirae. J Biol Chem. 1993 Jun 15;268(17):12775-9.

3(0,0,0,3) Details
16044341 Kishimoto S, Kawazoe Y, Ikeno M, Saitoh M, Nakano Y, Nishi Y, Fukushima S, Takeuchi Y: Role of Na+, K+-ATPase alpha1 subunit in the intracellular accumulation of cisplatin. Cancer Chemother Pharmacol. 2006 Jan;57(1):84-90. Epub 2005 Nov 5.

2(0,0,0,2) Details
10593600 Vasic V, Jovanovic D, Krstic D, Nikezic G, Horvat A, Vujisic L, Nedeljkovic N: Prevention and recovery of CuSO4-induced inhibition of Na+/K+ -ATPase and Mg2+ -ATPase in rat brain synaptosomes by EDTA. Toxicol Lett. 1999 Oct 29;110(1-2):95-104.


Enzymatic activities of Na+/K+-ATPase and Mg2+ -ATPase from rat brain synaptic plasma membrane were studied in the absence and presence of EDTA.
1(0,0,0,1) Details
16158233 Magnani D, Solioz M: Copper chaperone cycling and degradation in the regulation of the cop operon of Enterococcus hirae. Biometals. 2005 Aug;18(4):407-12.


The cop operon of E. hirae consists of four genes that encode a repressor, CopY, a copper chaperone, CopZ, and two CPx-type copper ATPases, CopA and CopB.
1(0,0,0,1) Details
11085262 Zhang Y, Jock S, Geider K: Genes of Erwinia amylovora involved in yellow color formation and release of a low-molecular-weight compound during growth in the presence of copper ions. Mol Gen Genet. 2000 Oct;264(3):233-40.

Most Erwinia amylovora strains form yellow mucoid colonies on solid minimal medium containing asparagine and copper sulfate (MM2Cu).
The putative protein YcfA shows low homology with K+/Na+ channel transporter ATPases.
1(0,0,0,1) Details