Protein Information

Name IRP2
Synonyms ACO 3; ACO3; IRE BP 2; IRE binding protein 2; IREB 2; IREB2; IRP 2; IRP2…

Compound Information

Name cycloheximide
CAS

Reference List

PubMed Abstract RScore(About this table)
16479012 Wang J, Fillebeen C, Chen G, Andriopoulos B, Pantopoulos K: Sodium nitroprusside promotes IRP2 degradation via an increase in intracellular iron and in the absence of S nitrosylation at C178. Mol Cell Biol. 2006 Mar;26(5):1948-54.

Actinomycin D, cycloheximide, succinylacetone, and dimethyl-oxalylglycine antagonize IRP2 degradation in response to both FAC and SNP, suggesting a common mechanistic basis.
84(1,1,1,4) Details