| Name | erythropoietin |
|---|---|
| Synonyms | EP; EPO; Epoetin; Erythropoietin; Erythropoietin precursor; Epoetins; Erythropoietins; Erythropoietin precursors |
| Name | copper sulfate |
|---|---|
| CAS | sulfuric acid copper(2+) salt (1:1) |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 16025538 | Kim YK, Shin HS, Tomiya N, Lee YC, Betenbaugh MJ, Cha HJ: Production and N-glycan analysis of secreted human erythropoietin glycoprotein in stably transfected Drosophila S2 cells. Biotechnol Bioeng. 2005 Nov 20;92(4):452-61. After copper sulfate induction, transfected S2 cells were found to secrete hEPO with a maximum expression level of 18 mg/L and a secretion efficiency near 98%. |
2(0,0,0,2) | Details |
| 16595992 | Higuchi T, Matsukawa Y, Okada K, Oikawa O, Yamazaki T, Ohnishi Y, Fujita T, Fukuda N, Soma M, Matsumoto K: Correction of copper deficiency improves erythropoietin unresponsiveness in hemodialysis patients with anemia. Intern Med. 2006;45(5):271-3. Epub 2006 Apr 3. |
2(0,0,0,2) | Details |
| 17963934 | Kim KR, Kim YK, Cha HJ: Recombinant baculovirus-based multiple protein expression platform for Drosophila S2 cell culture. J Biotechnol. 2008 Jan 1;133(1):116-22. Epub 2007 Sep 21. Based on the fact that baculovirus cannot replicate in nonpermissive Drosophila melanogaster Schneider line 2 (S2) cells, S2 cells that stably express human erythropoietin (hEPO) under the control of the S2-derived inducible metallothionein (MT) promoter were infected with three types of recombinant baculoviruses, each of which expressed a different fluorescent protein gene under the control of MT promoter. Addition of copper sulfate as an inducer to infected, stably transfected S2 cells resulted in simultaneous expression of hEPO and three fluorescent proteins. |
1(0,0,0,1) | Details |
| 304669 | Zidar BL, Shadduck RK, Zeigler Z, Winkelstein A: Observations on the anemia and neutropenia of human copper deficiency. . Am J Hematol. 1977;3:177-85. Copper sulfate therapy was followed by a marked reticulocytosis, increase in hematocrit, and recovery of neutrophils. Additional studies indicated that both serum and urinary erythropoietin values were low; serum activity increased after supplementation. |
1(0,0,0,1) | Details |