Protein Information

Name galectin 8
Synonyms Gal 8; Galectin 8; LGALS 8; LGALS8; PCTA 1; PCTA1; Po66 carbohydrate binding protein; Po66 CBP…

Compound Information

Name cycloheximide
CAS

Reference List

PubMed Abstract RScore(About this table)
15753078 Arbel-Goren R, Levy Y, Ronen D, Zick Y: Cyclin-dependent kinase inhibitors and JNK act as molecular switches, regulating the choice between growth arrest and apoptosis induced by galectin-8. J Biol Chem. 2005 May 13;280(19):19105-14. Epub 2005 Mar 7.

When p21 expression was inhibited by cycloheximide, galectin-8 directed the cells toward apoptosis, which involves induction of poly (ADP-ribose) polymerase cleavage.
39(0,1,1,9) Details