Protein Information

Name RPD3
Synonyms CDA07; RPD 3; RPD3; HD8; HDAC 8; HDAC8; HDACL 1; HDACL1…

Compound Information

Name cycloheximide
CAS

Reference List

PubMed Abstract RScore(About this table)
18205807 Borecka-Melkusova S, Kozovska Z, Hikkel I, Dzugasova V, Subik J: RPD3 and ROM2 are required for multidrug resistance in Saccharomyces cerevisiae. FEMS Yeast Res. 2008 May;8(3):414-24. Epub 2008 Jan 16.

In this work, it is shown that the RPD3 gene encoding the histone deacetylase that functions as a transcriptional corepressor at many promoters and the ROM2 gene coding for the GDP/GTP exchange protein for Rho1p and Rho2p participating in signal transduction pathways are required for PDR5 transcription under cycloheximide-induced and noninduced conditions.
33(0,1,1,3) Details