| Name | TORC1 |
|---|---|
| Synonyms | CREB regulated transcription coactivator 1; CRTC 1; CRTC1; MECT 1; MECT1; Mucoepidermoid carcinoma translocated 1; Mucoepidermoid carcinoma translocated protein 1; TORC 1… |
| Name | cycloheximide |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19684113 | Huber A, Bodenmiller B, Uotila A, Stahl M, Wanka S, Gerrits B, Aebersold R, Loewith R: Characterization of the rapamycin-sensitive phosphoproteome reveals that Sch9 is a central coordinator of protein synthesis. Genes Dev. 2009 Aug 15;23(16):1929-43. The target of rapamycin complex 1 (TORC1) is an essential multiprotein complex conserved from yeast to humans. |
3(0,0,0,3) | Details |
| 18030348 | Thedieck K, Polak P, Kim ML, Molle KD, Cohen A, Jeno P, Arrieumerlou C, Hall MN: PRAS40 and PRR5-like protein are new mTOR interactors that regulate apoptosis. PLoS One. 2007 Nov 21;2(11):e1217. TOR is found in two functionally and structurally distinct multiprotein complexes termed TOR complex 1 (TORC1) and TOR complex 2 (TORC2). HeLa cells in which PRAS40 was knocked down were protected against induction of apoptosis by TNFalpha and cycloheximide. |
1(0,0,0,1) | Details |
| 19244510 | Li S, Zhang C, Takemori H, Zhou Y, Xiong ZQ: TORC1 regulates activity-dependent CREB-target gene transcription and dendritic growth of developing cortical neurons. J Neurosci. 2009 Feb 25;29(8):2334-43. |
6(0,0,0,6) | Details |
| 19748353 | Binda M, Peli-Gulli MP, Bonfils G, Panchaud N, Urban J, Sturgill TW, Loewith R, De Virgilio C: The Vam6 GEF controls TORC1 by activating the EGO complex. . Mol Cell. 2009 Sep 11;35(5):563-73. |
5(0,0,0,5) | Details |
| 19328065 | Lempiainen H, Uotila A, Urban J, Dohnal I, Ammerer G, Loewith R, Shore D: Sfp1 interaction with TORC1 and Mrs6 reveals feedback regulation on TOR signaling. Mol Cell. 2009 Mar 27;33(6):704-16. |
4(0,0,0,4) | Details |
| 17698581 | Shen C, Lancaster CS, Shi B, Guo H, Thimmaiah P, Bjornsti MA: TOR signaling is a determinant of cell survival in response to DNA damage. Mol Cell Biol. 2007 Oct;27(20):7007-17. Epub 2007 Aug 13. The conserved TOR (target of rapamycin) kinase is part of a TORC1 complex that regulates cellular responses to environmental stress, such as amino acid starvation and hypoxia. |
4(0,0,0,4) | Details |