Protein Information

Name Nle
Synonyms HUSSY 07; NLE 1; NLE1; Nle; Notchless homolog 1; WD repeat protein HUSSY 07; notchless homolog 1 (Drosophila); Nles…

Compound Information

Name cycloheximide
CAS

Reference List

PubMed Abstract RScore(About this table)
18647593 Ozaki Y, Kato T, Kitagawa M, Fujita H, Kitagawa S: Calpain inhibition delays neutrophil apoptosis via cyclic AMP-independent activation of protein kinase A and protein kinase A-mediated stabilization of Mcl-1 and X-linked inhibitor of apoptosis (XIAP). Arch Biochem Biophys. 2008 Sep 15;477(2):227-31. Epub 2008 Jul 11.

Calpain inhibitors (PD150606 and N-acetyl-Leu-Leu-Nle-CHO) prevented spontaneous neutrophil apoptosis and degradation of Mcl-1 and XIAP, and the effects of calpain inhibitors on neutrophils were resistant to cycloheximide.
81(1,1,1,1) Details