| PubMed |
Abstract |
RScore(About this table) |
| 17308068 |
Bachmann M, Dragoi C, Poleganov MA, Pfeilschifter J, Muhl H: Interleukin-18 directly activates T-bet expression and function via p38 mitogen-activated protein kinase and nuclear factor-kappaB in acute myeloid leukemia-derived predendritic KG-1 cells. Mol Cancer Ther. 2007 Feb;6(2):723-31.
Blockage of translation by cycloheximide, usage of neutralizing antibodies, and the inability of IFNgamma to mediate significant p38 mitogen-activated protein kinase activation in KG-1 cells clearly revealed that activation of T-bet was not via autocrine IFNgamma. |
6(0,0,0,6) |
Details |
| 16951314 |
Li H, Wojciechowski W, Dell'Agnola C, Lopez NE, Espinoza-Delgado I: IFN-gamma and T-bet expression in human dendritic cells from normal donors and cancer patients is controlled through mechanisms involving ERK-1/2-dependent and IL-12-independent pathways. J Immunol. 2006 Sep 15;177(6):3554-63.
Treatment of DC with cycloheximide revealed that bryostatin-1-induced T-bet expression requires de novo protein synthesis, but bryostatin-1-induced IFN-gamma expression is independent of protein synthesis. |
13(0,0,1,8) |
Details |
| 16237056 |
Park IK, Shultz LD, Letterio JJ, Gorham JD: TGF-beta1 inhibits T-bet induction by IFN-gamma in murine CD4+ T cells through the protein tyrosine phosphatase Src homology region 2 domain-containing phosphatase-1. J Immunol. 2005 Nov 1;175(9):5666-74.
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4(0,0,0,4) |
Details |