| Name | TLR3 |
|---|---|
| Synonyms | CD283; CD283 antigen; TLR 3; TLR3; Toll like receptor 3; Toll like receptor 3 precursor; CD283 antigens; Toll like receptor 3s… |
| Name | cycloheximide |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 18199340 | Jiang Q, Wei H, Tian Z: Poly I:C enhances cycloheximide-induced apoptosis of tumor cells through TLR3 pathway. BMC Cancer. 2008 Jan 17;8:12. RESULTS: We show that TLR3 are widely expressed on human and murine tumor cell lines, and activation of TLR3 signaling in cancerous cells by poly I:C made Hela cells (human cervical cancer) and MCA38 cells (murine colon cancer) become dose-dependently sensitive to protein synthesis inhibitor cycloheximide (CHX)-induced apoptosis. |
43(0,1,2,8) | Details |
| 16237104 | Mandal P, Novotny M, Hamilton TA: Lipopolysaccharide induces formyl peptide receptor 1 gene expression in macrophages and neutrophils via transcriptional and posttranscriptional mechanisms. J Immunol. 2005 Nov 1;175(9):6085-91. Elevated FPR1 mRNA expression is also induced in response to ligands for TLR2 and TLR3. First, the response to LPS is partially blocked by the translational inhibitor cycloheximide. |
1(0,0,0,1) | Details |
| 17082634 | Kato A, Truong-Tran AQ, Scott AL, Matsumoto K, Schleimer RP: Airway epithelial cells produce B cell-activating factor of TNF family by an IFN-beta-dependent mechanism. J Immunol. 2006 Nov 15;177(10):7164-72. Induction of BAFF by dsRNA was dependent upon protein synthesis and IFN-alphabeta receptor-JAK-STAT signaling, as indicated by studies with cycloheximide, the JAK inhibitor I, and small interfering RNA against STAT1 and IFN-alphabeta receptor 2. |
0(0,0,0,0) | Details |
| 16790802 | Bennouna S, Sukhumavasi W, Denkers EY: Toxoplasma gondii inhibits toll-like receptor 4 ligand-induced mobilization of intracellular tumor necrosis factor alpha to the surface of mouse peritoneal neutrophils. Infect Immun. 2006 Jul;74(7):4274-81. In contrast to intermediate inhibitory effects in nontreated neutrophils, T. gondii induced a complete blockade in LPS-induced surface TNF-alpha expression in the presence of the protein synthesis inhibitor cycloheximide. |
0(0,0,0,0) | Details |