Protein Information

Name TNFR 2
Synonyms CD120b; p75; CD120b antigen; Etanercept; TBPII; TNF R II; TNF R2; TNF R75…

Compound Information

Name cycloheximide
CAS

Reference List

PubMed Abstract RScore(About this table)
15545300 Jaruga-Killeen E, Rayford W: TNF receptor 1 is involved in the induction of apoptosis by the cyclin dependent kinase inhibitor p27Kip1 in the prostate cancer cell line PC-3. FASEB J. 2005 Jan;19(1):139-41. Epub 2004 Nov 15.

Cell cycle and typical markers of apoptosis were analyzed by flow cytometry in the presence of the following reagents: cycloheximide, pan-caspase inhibitor ZVAD-fmk, neutralizing anti-TNFR1, and anti-TNFR2.
82(1,1,1,2) Details
19473970 Ding B, Kirkiles-Smith NC, Pober JS: FOXO3a regulates oxygen-responsive expression of tumor necrosis factor receptor 2 in human dermal microvascular endothelial cells. J Biol Chem. 2009 Jul 17;284(29):19331-9. Epub 2009 May 27.


Microvascular endothelial cell (EC) expression of tumor necrosis factor receptor (TNFR) 2 is induced in situ by ischemia/reperfusion injury.
7(0,0,0,7) Details
15657078 Depuydt B, van Loo G, Vandenabeele P, Declercq W: Induction of apoptosis by TNF receptor 2 in a T-cell hybridoma is FADD dependent and blocked by caspase-8 inhibitors. J Cell Sci. 2005 Feb 1;118(Pt 3):497-504. Epub 2005 Jan 18.


Previously we reported that both human TNFR1 and TNFR2 mediate TNF-induced apoptosis in the transfected rat/mouse T cell hybridoma PC60.
5(0,0,0,5) Details