Protein Information

Name KLF5
Synonyms BTE binding protein 2; BTEB 2; BTEB2; Basic transcription element binding protein 2; CKLF; Colon krueppel like factor; Colon kruppel like factor; GC box binding protein 2…

Compound Information

Name cycloheximide
CAS

Reference List

PubMed Abstract RScore(About this table)
19411256 Liu R, Zheng HQ, Zhou Z, Dong JT, Chen C: KLF5 promotes breast cell survival partially through fibroblast growth factor-binding protein 1-pERK-mediated dual specificity MKP-1 protein phosphorylation and stabilization. J Biol Chem. 2009 Jun 19;284(25):16791-8. Epub 2009 May 1.

By cycloheximide chase assays, we found that KLF5 decreases MKP-1 protein degradation via activating the ERK signaling.
45(0,1,1,15) Details
15735697 Chen C, Sun X, Ran Q, Wilkinson KD, Murphy TJ, Simons JW, Dong JT: Ubiquitin-proteasome degradation of KLF5 transcription factor in cancer and untransformed epithelial cells. Oncogene. 2005 May 5;24(20):3319-27.

5(0,0,0,5) Details