| Name | cytochrome P450 1B1 |
|---|---|
| Synonyms | CP1B; CYP1B1; CYPIB 1; CYPIB1; Cytochrome P450 1B1; GLC3A; Cytochrome P450 1B1s |
| Name | cycloheximide |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 15837795 | Beischlag TV, Perdew GH: ER alpha-AHR-ARNT protein-protein interactions mediate -dependent transrepression of dioxin-inducible gene transcription. J Biol Chem. 2005 Jun 3;280(22):21607-11. Epub 2005 Apr 18. Both AHR and ARNT were capable of interacting directly with ER alpha, as ascertained by glutathione S-transferase pull-down. 17Beta- repressed TCDD-activated Cyp1a1 and Cyp1b1 gene transcription in MCF-7 cells in the presence of cycloheximide, as determined by reverse transcription/real-time PCR. |
31(0,1,1,1) | Details |
| 17257637 | Akintobi AM, Villano CM, White LA: 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) exposure of normal human dermal fibroblasts results in AhR-dependent and -independent changes in gene expression. Toxicol Appl Pharmacol. 2007 Apr 1;220(1):9-17. Epub 2006 Dec 15. Our data show that normal human dermal fibroblasts (NHDFs) are responsive to TCDD, as demonstrated by induction of cytochrome p450 1B1 (CYP1B1) expression. TCDD-repression of Id-1 and -3 is independent of de novo protein synthesis; co-treatment with cycloheximide has no effect on TCDD inhibition of Id-1 and Id-3. |
1(0,0,0,1) | Details |