| Name | GATA 2 |
|---|---|
| Synonyms | Endothelial transcription factor GATA 2; GATA binding protein 2; GATA 2; GATA2; NFE1B; GATA binding protein 2s |
| Name | cycloheximide |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 15966900 | Minegishi N, Suzuki N, Kawatani Y, Shimizu R, Yamamoto M: Rapid turnover of GATA-2 via ubiquitin-proteasome protein degradation pathway. Genes Cells. 2005 Jul;10(7):693-704. Since treatment of the cells with the proteasome inhibitor MG132 or clasto-Lactacystin substantially abrogated the effects of cycloheximide and UV-C irradiation and increased the expression level of both endogenous and transfected GATA-2, the degradation of GATA-2 seems to occur through the proteasome pathway. |
94(1,1,2,9) | Details |
| 18154321 | Lurie LJ, Boyer ME, Grass JA, Bresnick EH: Differential GATA factor stabilities: implications for chromatin occupancy by structurally similar transcription factors. Biochemistry. 2008 Jan 22;47(3):859-69. Epub 2007 Dec 23. Whereas the transcription factors GATA-1 and GATA-2 function both uniquely and redundantly to control blood cell development, the process termed hematopoiesis, mechanisms underlying their unique versus common functions are poorly understood. |
6(0,0,0,6) | Details |
| 19036901 | Magklara A, Smith CL: A composite intronic element directs dynamic binding of the progesterone receptor and GATA-2. Mol Endocrinol. 2009 Jan;23(1):61-73. Epub 2008 Nov 26. Our experiments revealed FKBP5 as a direct target of the PR, because it exhibited a rapid activation by that was cycloheximide independent and correlated with recruitment of RNA polymerase II to the promoter. |
3(0,0,0,3) | Details |