| Name | SSAT |
|---|---|
| Synonyms | DC21; Diamine acetyltransferase; Diamine acetyltransferase 1; KFSD; Polyamine N acetyltransferase 1; Putrescine acetyltransferase; SAT; SAT protein… |
| Name | cycloheximide |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 16637064 | Choi W, Proctor L, Xia Q, Feng Y, Gerner EW, Chiao PJ, Hamilton SR, Zhang W: Inactivation of IkappaB contributes to transcriptional activation of / N (1)-acetyltransferase. Mol Carcinog. 2006 Sep;45(9):685-93. /spermine N (1)-acetyltransferase (SSAT) is a key enzyme in polyamine catabolism. |
8(0,0,0,8) | Details |
| 17690107 | Butcher NJ, Broadhurst GM, Minchin RF: Polyamine-dependent regulation of spermidine-spermine N1-acetyltransferase mRNA translation. J Biol Chem. 2007 Sep 28;282(39):28530-9. Epub 2007 Aug 9. By contrast, cycloheximide completely inhibited induction by DENSPM, indicating a requirement for new protein synthesis. |
7(0,0,0,7) | Details |
| 19097065 | Stanic' I, Facchini A, Borzi RM, Stefanelli C, Flamigni F: The polyamine analogue N1,N11-diethylnorspermine can induce chondrocyte apoptosis independently of its ability to alter metabolism and levels of natural polyamines. J Cell Physiol. 2009 Apr;219(1):109-16. Treatment of human C-28/I2 chondrocytes with N (1),N (11)-diethylnorspermine (DENSPM), a polyamine analogue with clinical relevance as an experimental anticancer agent, rapidly induced / N (1)-acetyltransferase (SSAT) and spermine oxidase (SMO), key enzymes of polyamine catabolism and down-regulated ornithine decarboxylase, the first enzyme of polyamine biosynthesis, thus depleting all main polyamines within 24 h. |
2(0,0,0,2) | Details |